摘要
目的:探讨干扰素肌注及雾化吸入治疗小儿病毒性呼吸道感染的临床疗效。方法:2013年6月-2014年6月收治病毒性呼吸道感染患儿240例,年龄3个月~12岁,随机分为A、B、C组,各80例。A组应用重组人干扰素-α1b肌注,B组应用重组人干扰素-α1b雾化治疗,C组使用其他药物雾化吸入,比较3组的临床疗效。结果:B组的治疗总有效率(93.75%)显著高于A组(86.25%)和C组(78.75%),差异具有统计学意义(P<0.05)。B组的退热时间与A组和C组比较显著缩短,差异具有统计学意义(P<0.05)。治疗过程中均未见不良反应。结论:干扰素雾化治疗小儿病毒性呼吸道感染疗效显著,不良反应少,值得在临床中推广应用。
Objective:To explore the curative effect comparing of interferon intramuscular injection and atomizing in the treatment of pediatric viral respiratory infection.Methods:240 cases of children with viral respiratory infection aged 3~12 years old from June 2013 to June 2014 were randomly divided into group A,B,C group with 80 cases in each group.Group A accepted epoetin interferon alpha 1b intramuscular injection;group B accepted epoetin interferon alpha 1 B atomization treatment;group C accepted other atomization inhalation.We compared the clinical effect of the three groups.Results: The total effective rate of group B(93.75) was significantly higher than that of group A(86.25) and group C(78.75),and the difference was statistically significant(P<0.05).Compared with group A and group C,the defervescence time of group B was significantly shortened, with statistically significant difference(P<0.05).Treatment of adverse reaction was not found in the process.Conclusion:The therapeutic effect of interferon atomization in the treatment of infantile viral respiratory infection is obvious and has few adverse reactions,which is worthy of clinical popularization and application.
关键词
病毒性呼吸道感染
小儿
干扰素
临床疗效
Viral respiratory infection
Children
Interferon
Clinical curative effect
