摘要
目的:了解瑞芬太尼联合普鲁泊福与芬太尼联合普鲁泊福两种麻醉方式在神经外科手术中的临床应用效果差异。方法:2010-2013年收治应用瑞芬太尼联合普鲁泊福麻醉方式患者50例,设为A组,另选本院同期收治应用芬太尼联合普鲁泊福麻醉方式患者50例,设为B组。对比两组患者苏醒时间、普鲁泊福诱导量、普鲁泊福总用量等各项临床指标以及血液动力学。结果:相对于B组,A组在苏醒时间、普鲁泊福诱导量、普鲁泊福总用量等各项指标均有显著优越性,差异存在统计学意义(P<0.05);对比两组患者各个时间段的舒张压、收缩压和心率,除诱导麻醉前无显著差异,其余各时间段A组均显著优于B组,差异存在统计学意义(P<0.05)。结论:在神经外科手术中应用瑞芬太尼联合普鲁泊福,其麻醉效果和血液动力学影响相对于芬太尼联合普鲁泊福均有明显优越性,不但能够保障患者手术的顺利完成且不会对患者术后生活质量造成严重影响,具有可靠高效的优点,值得临床推广。
Objective:To understand the difference of the clinical application effects of two kinds of anesthesia remifentanil or fentanyl combined with propofol in neurosurgery operation.Methods:50 patients with the application of remifentanil combined with propofol anesthesia method were selected from 2010 to 2013 as A group.50 patients with the application of fentanyl combined with propofol anesthesia method were selected at the same time in this hospital as B group.The clinical indicators,such as the awakening time,propofol induction quantity,propofol total amount and haemodynamics of two groups were compared.Results:Compared with B group,the clinical indicators,such as the awakening time,propofol induction quantity and propofol total amount of patients in A group had significant superiority,and the difference had statistical significance(P<0.05).The diastolic blood pressure,systolic blood pressure and heart rate of each time period of patients in two groups were compared,in addition to before induction of anesthesia had no statistical difference,the rest of A group were significantly better than those of B group,and there were significant differences(P<0.05).Conclusion:Compared with fentanyl combined with propofol,the application of remifentanil combined with propofol in neurosurgery operation has the obvious superiority on the anesthetic effect and hemodynamic effect.It not only can guarantee the successful completion of the operation in patients,but also has seriously impact on the postoperative life quality of patients.It has the advantages of high efficiency and reliable.It is worthy of clinical application.
