摘要
目的:探讨妊娠合并血小板减少的病因及分娩方式。方法:回顾性分析85例妊娠合并血小板减少患者的诊断、治疗以及分娩方式。结果:分析妊娠合并血小板减少病因得出,妊娠相关性免疫血小板减少症35例,再生障碍性贫血12例,妊娠期高血压疾病10例,巨幼细胞性贫血10例,免疫性血小板减少性紫癜8例,其他血液或免疫性疾病5例。血小板水平减少至20×109/L以下30例(35.21%),主要以再生障碍性贫血为主,血小板水平减少(20~50)×109/L 40例,以特发性血小板减少为主。血小板水平减少(50~100)×109/L 15例,以特发性血小板减少为主。85例病例中,妊娠晚期终止70例,其中自然分娩20例,剖宫产50例,其中血小板水平减少至20×109/L以下29例,剖宫产分娩23例,血小板水平减少(20~50)×109/L 25例,剖宫产分娩20例(80.25%),血小板水平减少(50-100)×109/L 16例,剖宫产分娩12例。结论:妊娠相关性免疫血小板减少症是最常见的妊娠合并血小板减少症类型,产时对母儿无明显危害,其主要治疗方式:病因治疗、使用糖皮质激素及血小板制剂。
Objective:To investigate the etiology of thrombocytopenia in pregnancy and childbirth way.Methods:Retrospective analysis of 85 cases of diagnosis,therapy of patients with PT and the mode of delivery.Results:Analysis of the etiology of PT that, 35 cases of pregnancy associated immune thrombocytopenia,12 cases of aplastic anemia,10 cases of hypertensive disorders in pregnancy,10 cases of megaloblastic anemia,8 patients with immune thrombocytopenic purpura,5 cases of other blood and immune diseases.30 cases of platelet levels decreased to less than 20×109/L(35.21%),mainly in aplastic anemia,40 cases of platelet levels decreased(20~50)×109/L,with idiopathic thrombocytopenia.15 cases of platelet levels decreased(50~100)×109/ L,with idiopathic thrombocytopenia.Among the 85 cases,70 cases of late pregnancy termination,including 20 cases of natural childbirth,cesarean section in 50 cases,including 29 cases of platelet levels decreased to less than 20×109/L,23 cases of cesarean section,25 cases of platelet levels decreased(20~50) ×109/L,20 cases of cesarean section(80.25%) in 16 cases,platelet levels decreased(50~100) × 109/L,12 cases of cesarean section.Conclusion:The correlation between immune platelet pregnancy syndrome is the most common pregnancy with platelet reduce disease type,no obvious harm to mother and infant birth,the main therapeutic methods:etiological treatment,the use of glucocorticoid and platelet preparations.
关键词
妊娠
血小板减少
临床分析
Pregnancy
Thrombocytopenia
Clinical analysis