摘要
目的:探讨硫酸镁在妊娠期高血压轻度子痫前期中应用的价值。方法:收治轻度子痫前期患者72例,随机分为两组。两组均一般处理,包括保证休息,间断吸氧合理饮食,必要时加地西泮镇静。一组为常规应用硫酸镁。观察指标:发展为重度子痫前期,胎动减少发生率,新生儿1分钟评分,5分钟评分。8例因要求出院,未能继续治疗,退出研究。发展至重度子痫前期的:实验组4/34,对照组3/30,差异无统计学意义(P>0.05)。胎动减少发生率:实验组62.6%,对照组20%,差异有统计学意义(P<0.05)。新生儿1分钟评分:实验组7.9±1.4分,对照组8.0±1.6分,差异无统计学意义(P>0.05)。5分钟评分实验组8.6±0.5分,对照组8.7±0.6分,差异无统计学意义(P>0.05)。结论:在妊娠期高血压轻度子痫前期中应用硫酸镁的价值较小,意义有待于进一步探讨。
Objective:To explore application value of Magnesium sulfate in mild preeclampsia induced by hypertension during pregnancy.Methods:We selected 72 patients with mild preeclampsia during 2011 January to 2013 January,these patients were randomly divided into two groups.Two groups were treated with general treatment,including to ensure the rest,intermittent oxygen, reasonable diet,and with diazepam sedation if necessary.A group was treated with Magnesium sulfate regularly.Observation index: the development of severe preeclampsia,the incidence of fetal movement reducing,score of 1 minute of neonatus,score of 5 minutes of neonatus.8 patients withdrew from the study because of discharge.The development to the severe preeclampsia: experimental group with 4/34,control group with 3/30,there was no significant difference(P>0.05).The incidence of fetal movement reducing:experimental group with 62.6%,control group with 20%,there was significant difference(P<0.05).Score of 1 minutes of neonatus:experimental group with 7.9±1.4,control group with 8±1.6,There was no significant difference(P>0.05). Score of 5 minutes of neonatus:The experimental group was 8.6 ± 0.5,control group 8.7 ± 0.6,and there was no significant difference(P>0.05).Conclusion:The application value of Magnesium sulfate in mild preeclampsia induced by hypertension during pregnancy is small.The application value of the Magnesium sulfate is worthy of further study.
关键词
轻度子痫前期
硫酸镁
价值
Mild preeclampsia
Magnesium sulfate
Value
