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肝切除和腹腔灌洗化疗治疗大肠癌肝转移

Clinical treatment of colorectal carcinoma by hepatectomy in combination with intraoperative intraperitoneal chemotherapy in 24 cases of colorectal carcinoma
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摘要 目的 总结联合肝叶切除并温热低渗腹腔灌洗化疗治疗大肠癌的经验。方法 对1 993年~ 1 997年间施行联合肝叶切除并温热低渗腹腔灌洗化疗的 2 4例大肠癌的临床资料进行回顾性分析。结果 本组 2 4例术后无严重并发症发生 ,手术死亡率为 0。随访 1、3、5年生存率分别为79 .2 %、4 1 .7%、2 9.2 %。结论 掌握联合脏器切除的指征、关注腹腔内脱落癌细胞的处理、提高手术技巧、注重围手术期的营养支持是降低并发症发生率 。 Objective To evaluate the clinical application of hepatectomy in combination with intraoperative interaperitoneal hyperthermochemotherapy (IOIPHTC) for colorectal carcinoma (CRC).Methods The treatment and therapeutic effect of 24 cases of CRC undergoing hepatectomy in combination with IOIPHTC from 1993 to 1997 were analyzed retrospectively.Results Of all cases,no severe complication occurred;the operative mortality was zero;the survival rate for 1 ,3 ,and 5 years was 79.2% , 41.7% and 29.2% respectively during follow up.Conclusion The important factors for reducing operative morbidity and improving operative successful and long term survival rate are as follows:(1)To grasp the indications of allied hepatectomy;(2)To dispose the isolated intraperitoneal cancer cells;(3)To improve the surgical skills;(4)To value patient's perioperative nutritional support.
作者 范平
出处 《腹部外科》 2003年第6期353-354,共2页 Journal of Abdominal Surgery
关键词 肝切除 腹腔灌洗化疗 联合治疗 大肠癌 肝转移 Intestine,large Neoplasms Hepatectomy Drug therapy,combination
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