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survivin与妇科恶性肿瘤

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摘要 survivin是近年来发现的凋亡抑制蛋白(IAP)家族的新成员,具有双重功能:既能抑制细胞凋亡,又可以调节有丝分裂。它选择性表达于常见的多种恶性肿瘤,而在正常组织和成人分化组织中并不表达,因此可作为一个潜在的药物靶向,同时又与肿瘤的发病机制、化疗及预后密切相关,有着极为广阔的应用前景。
出处 《国外医学(妇产科学分册)》 2003年第6期375-378,共4页 Foreign Medical Sciences(Obstet Gynecol Fascicle)
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