摘要
目的探讨饮酒对血脂、血糖、血清白蛋白含量的影响及其与脂肪肝发病的联系。方法将连续性体检男性人群分成非酒精组、白酒组及啤酒组 ,按日均饮酒量及饮酒时间又将白酒组及啤酒组再次分组 ,对比分析各组高脂血症、高糖血症及低白蛋白血症检出率。结果非酒精组及白酒组脂肪肝者较非脂肪肝者、啤酒组较非酒精组及白酒组非脂肪肝与脂肪肝者、5 0～ 10 0 g白酒组较非酒精组及 >10 0 g白酒组脂肪肝者、5 0～ 10 0 g白酒组较非酒精组非脂肪肝者高脂血症检出率明显增高 ,白酒组较非酒精组非脂肪肝及脂肪肝者低白蛋白血症检出率均明显增高 (P<0 .0 5～ 0 .0 0 1)。随着日均饮酒量增加 ,白酒组非脂肪肝与脂肪肝者低白蛋白血症检出率均有显著增高 (χ2 =6 .5 8,P<0 .0 5 ;χ2 =10 .0 5 ,P<0 .0 1)。而啤酒组非脂肪肝者及脂肪肝者高糖血症检出率与饮酒时间之间呈现出显著的正相关关系 (χ2 =11.4 6 ,P<0 .0 1;χ2 =7.0 2 ,P<0 .0 5 )。结论饮酒导致高脂血症或高糖血症参与酒精性脂肪肝的发病机制 ,以啤酒组中该作用机制最为明显 ,而在 >10 0 g白酒组脂肪肝的发病机制中有营养不良所致低蛋白血症这一因素参与。
Objective To explore the effect and its clinical significance of alcohol on hyperlipideamia,hyperglycemia and hypoalbuminemia.Methods All peoples after physical examination were divided into non-alcohol group,liquor group(including daily drink amount <50 g,50～100 g and >100 g three groups.And <5 years,5～10 years and >10years three groups) and beer group (include daily drink amount <250 ml,250～500 ml and >500 ml three groups,<5 years, 5～10 years and >10 years three groups).The incidence of hyperlipideamia,hyperglycemia and hypoalbumineamia in each group were compared.Results The incidence of hyperlipideamia was much higher in non-alcohol group and liquor group with fatty liver disease than that without fatty liver disease,higher in beer group than that in non-alcohol group or in liquor group,in 50~100 g liquor group than that in non alcohol group and >100 g liquor group with fatty liver disease,in 50~100 liquor group than that in non alcohol group and >100 g liquor group with fatty liver diseases,and also in 50~100 g liquor group than that in non-alcohol group without fatty liver disease.The incidence of hypoalbumineamia was much higher in liquor group than that in non-alcohol group.There were significantly positive relationships between the incidence of hypoalbumineamia and daily drink amount in liquor group,hyperglycemia and drink time in beer group.Conclusion Hyperlipideamia and hyperglycemia had similar pathological effect on fatty liver disease in beer group and in <50 g,50~100 g liquor groups as in non-alcohol group.Some fatty liver disease were caused by malnutrition in >100 g liquor group.
出处
《中国慢性病预防与控制》
CAS
2003年第6期243-245,共3页
Chinese Journal of Prevention and Control of Chronic Diseases
关键词
脂肪肝
饮酒
高脂血症
高糖血症
低白蛋白血症
Fatty liver disease
Alcohol
Non-alcohol
Beer
Liquor
Hyperlipideamia
Hyperglycemia
Hypoalbumineamia
