摘要
目的:观察比较新药普罗布考片与其它两种降血脂药的降脂作用。方法:197 例高脂血症患者随机分组,分别口服藻酸双酯钠片(100mg,tid) 、非诺贝特片(100mg.tid) 和普罗布考片(250mg.bid)。于第4 周、第8 周抽空腹血测定血脂值。结果:服药8 周后,普罗布考组降血清总胆固醇(TC)总有效率84 .4% ;藻酸双酯钠组和非诺贝特组分别为75.5 % 和75.9% 。服普罗布考期间,仅发现少而轻的不良反应。结论:普罗布考片为安全显效的降血脂药。
AIM To compare the effects of Probucol with polysaccharide sodium(p.s.s) and fenofibrate.METHODS The blood lipid was derermined in 197 patients with hyperlipidemia treated with probucol,p.s.s and fenofibrate after 4 and 8 weeks respectively.RESULTS The total effectve rate of probucol was 84.4%,while the effective rate of two other agent was 75.5 and 75.9% respectively.CONCLUSION Probucol tablets are safe and effective in lowering bloodlipid.
出处
《解放军药学学报》
CAS
1999年第4期21-22,F003,共3页
Pharmaceutical Journal of Chinese People's Liberation Army
基金
河北省经贸委重点科研项目