摘要
A HPLC method for determination of gatifloxacin and sodium chloride injection was presented. A Shim-Pack CLC-ODS column was used with mobile phase of 0.02 mol/L potassium dihydrogen phosphate buffer solution （ pH4.0 , adjusted with H3PO4）-acetonitrile （85∶15, containing 2 mmol/L tetrabutylammonium bromide） at detection wavelength of 292 nm . It had a good linearity over the concentration range of 4～ 32 μg/ml . The average recovery was 98.5% with RSD of 0.7% .
A HPLC method for determination of gatifloxacin and sodium chloride injection was presented. A Shim-Pack CLC-ODS column was used with mobile phase of 0.02 mol/L potassium dihydrogen phosphate buffer solution ( pH4.0 , adjusted with H_3PO_4)-acetonitrile (85∶15, containing 2 mmol/L tetrabutylammonium bromide) at detection wavelength of 292 nm . It had a good linearity over the concentration range of 4～ 32 μg/ml . The average recovery was 98.5% with RSD of 0.7% .
出处
《中国医药工业杂志》
CAS
CSCD
北大核心
2003年第11期579-580,共2页
Chinese Journal of Pharmaceuticals
