摘要
目的 了解老年期痴呆患者生存情况,分析影响其生存的有关因素。方法 对符合CC-MD—2诊断标准的145例老年期痴呆患者进行为期5年的随访研究,对影响生存的有关因素进行单因素分析和Cox回归分析。结果 老年期痴呆的5年生存率为49.19％,其中阿尔海默病(AD)和血管性痴呆(VD)分别为50.08％、47.23％。单因素分析显示慢性病史、MMSE值、治疗、精神病性症状、发病年龄、配偶照料等因素在生存组和死亡组中有显著差异。Cox回归分析显示,影响生存的主要因素有2项,按RR值大小为发病年龄和配偶照料。结论 老年期痴呆是高病死率疾病,分析影响生存的危险因素并加以干预,可以延长其生存时间。
Objective To investigate the living state of senile dementia, to analysis the available associated factors. Methods 145 patients who had met the criteria of CCMD-2 on dementia were selected and followed up for 5 years, focused on their social background data and statistical managed by Cox regression analysis. Results The survival rate of dementia was 49. 19% among 5 years, which the Alrheimers cases were a little better than the Vessel's cases (50. 08% VS 47. 23%). There were significant differences between survival and death cases on suffering from chronic disease, mental symptoms, onset age, consort's care, MMSE scores and treatment, the onset age and consort's care were the main influenced factors. Conclusions Senile dementia is a disease with high death rate. The survival period of these cases will be longer if their associated social background risks were managed or intervention.
出处
《神经疾病与精神卫生》
2003年第5期337-339,共3页
Journal of Neuroscience and Mental Health
