摘要
目的 观察评价阿莫西林 /克拉维酸钾与头孢拉定治疗急性细菌性感染的疗效及安全性。方法 14 2例患者随机分成 2组 ,治疗组 73例 ,用阿莫西林 /克拉维酸钾 0 .375～ 0 .75g ,po ,tid ;对照组 6 9例 ,用头孢拉定 0 .5～ 1.0 g ,po ,tid ;疗程均为 7～14d。结果 治疗组与对照组的临床总有效率分别为 91.8%和 91.3% ;细菌清除率分别为 89.8%和 88.6 % ;不良反应的发生率分别为 4 .1%和 4 .3% ;2组之间无显著性差异 (P >0 .0 5 )。结论 阿莫西林 /克拉维酸钾治疗急性细菌性感染疗效满意 ,安全方便 。
OBJECTIVE To evaluate the efficacy and safety of amoxicilli/clavulanate potassium and cefradine in treatment of acute bacterial infection. METHOD 142 patients were randomly divided into two groups:73 patients in the treatment group were trearted with amoxicilli/clavulanate potassium 0.375～0.75g, po , tid, for 7wk; as control, the other 69 patients in the control group were treated with cefradine, 0.5～0.1g, po , tid, for 7wk.RESULTS The total clinical effective in the control group rate was 91.8% in amoxicilli/clavulanate potassium group and 91.3% in cefradine group. The becteria clearance rate was 89.8% in amoxicilli/clavulanate potassium group and 88.6% in cefradine group; The adverse reactions rate was 4.1% in amoxicilli/clavulanate potassium group and 4.3% in cefradine group; the difference of the two groups was not significant ( P >0.05).CONCLUSION Amoxicilli/clavulanate potassium is safe and effective in treating acute bacterial infection and has no obvious adverse reaction.
出处
《中国现代应用药学》
CAS
CSCD
北大核心
2003年第5期420-422,共3页
Chinese Journal of Modern Applied Pharmacy
关键词
阿莫西林
克拉维酸钾
头孢拉定
细菌性感染
amoxicilli, clavulanate potassium, treatment, acute bacterial infection
