摘要
目的 探讨异体、异种脱细胞异体真皮基质与自体复合移植的可行性。方法 5例大面积Ⅲ度烧伤创面早期切痂 ,2例 3个部位采用异种脱细胞真皮基质移植 ,3例 3个部位采用同种脱细胞真皮基质移植 ,将基质缝合固定。微粒皮均匀涂布在异体皮的真皮面上 ,覆盖于创面上 ,缝合包扎固定。未移植脱细胞真皮基质的创面作对照观察 ,微粒皮与创面比例为 1:5。结果 异种脱细胞真皮基质移植部位表皮覆盖率 75 %。采用同种脱细胞真皮基质移植部位表面覆盖率 94%。随访时间最长 2年复合移植皮肤弹性好、无水胞和溃疡 ,愈合质量优于对照部位创面。结论 应用脱细胞异体真皮基质与自体微粒皮复合移植是可行性的 。
Objective To present the clinical application of composite graft of acellular heterogenous or allo-dermis matrix(ADM)with thin auto-microskin on burn wound Methods 5 inpatients with full thickness skin burn wounds were transplanted with 3 allo-ADM and 2 heterogenous ADM after eschar was excised,then the auto-microskin and allo-human skin were covered on the area of the matrix,the wound where no ADM grafting were covered as control groups only with auto-microskin and allo-human skin,The area of donor to wound is 1:5.Results Survived rate of 5 pieces composite skin that ADM with auto-microskin were grafted.After following up for two year,the skins of complex grifting had well elastic and smooth texture compared to auto-micrtoskin grafted.Conclusions The graft effectiveness of ADM and auto-microskin was better than that of auto-microskin,and this method could be used on major deep burn wound healing.
出处
《海南医学》
CAS
2003年第11期1-2,共2页
Hainan Medical Journal
基金
海南省自然科学基金资助项目 ( 80 0 0 6)
