摘要
应用国产氟啶酸治疗56例成人伤寒患者,剂量为每日3次,每次0.4g,疗程为10～14天。治疗结果临床有效率和细菌清除率均为100％,平均退热时间为3.6±1.6天。不良反应少见,对30例随访1年未见复发。国产氟啶酸治疗伤寒退热快、疗效高、复发率低、不良反应少、服用方便、价格相对较低,尤其适用于耐药株所致伤寒。
Enoxacin, a new fluoroquinolone, was given orally to treat 56 adult patients with typhoid fever at the dosage of 400mg tid for 10 to 14 days. The mean duration of defervescence was 86.5±39.0 hours (3.61±1.6 days), the rates of clinical effectiveness and bacteriological cure were both 100%. Thirty patients were followed up for one year after completion of therapy without relapse. These data suggested that enoxacin is the drug of choice in treating multiresistant Salmonella typhi infection, with the merits of quick respones, quick defervescence, low relapse rate, and convenience in use. The clinical efficacy of fluoroquinolones in treating typhoid fever is reviewed.
出处
《上海医学》
CAS
CSCD
北大核心
1992年第3期147-150,共4页
Shanghai Medical Journal
关键词
伤寒
氟啶酸
氟喹诺酮类
Typhoid fever
Enoxacin
Fluoroquinolones
