摘要
目的 18F -脱氧葡萄糖 (FDG)双探头符合线路SPECT显像全身检查 (DHC)对结肠直肠癌的转移和复发的临床价值 .方法 2 5例结肠直肠腺癌患者 ,均行胸部X线、上腹和盆腔CT、18F -FDG(DHC)全身检查 .结果 从检测病灶的部位 :①18F -FDG、CT肝 (≥ 1.4cm)分别为 4 5、4 7处 ,(p >0 .0 5 ) .当 (肝 )病灶小于 1.4cm ,18F -FDG未检出、而CT检出 6处 .②肠道、腹膜后、骶前分别为 2 4和 15处 (p <0 .0 5 ) ,其中 19例 2 0处 (DHC)经手术证实 .③其它骨骼分别为 11和 1处、但明显低于MDP的 2 6处 ,18F -FDG6例肺转移 17处病灶 ,X线为 13例 .④术吻合口分别为CT 3例和18F -FDG(DHC) 2例 ,手术证明复发 2例 ,CT其中 1例假阳性 (穿刺活检 )经治疗后复查病灶消失 .结论 18F -FDG对结肠直肠腺癌的原发、复发和转移部位在肠道、腹膜后、骶前及术吻合口较CT能早期、准确发现病灶 ,并制定临床分期 ,对于肝转移 ,18F -FDG未见明显优势 ,病灶小于 1.4cm ,18F -FDG未能检测出病灶 .
Objective Dual-head coincidence 18 F-FDG image on detecting recurrence and metastasis of colorectal cancer. Methods 25 patients finding with colorectal cancer were examined by CT on abdomen ,presacral and pelvis, 18 F-FDG total body image. Results In liver FDG showed 45 lesions. CT showed 47 (≥1.4cm)and 6 lesions (<1.4cm ). So there was no significant difference in liver (Lwsion≥1.4cm)(p>0.05). FDG couldn't find the lesion that was smaller than 1.4cm. But in the alimentary canal,retroperitoneum and anastomotic stoma,FDG was 24 and CT was 15.Clearly FDG was better than CT(p<0.05). CT had a false positive lesion in the anastomotic stoma. As the bone metastasis 18 F-FDG is 11 and better than CT, but less than MDP. And also FDG is 17 in lung, X-chest was 13. Conclusions 18 F-FDG is very useful in finding primary ,recurrence and metastases of colorectal cancer in the alimentary canal, retroperitoneum and anastomotic stoma. It is not better than CT exam in liver.Especially lesion less than 1.4cm, 18 F-FDG couldn't find the lesion in the liver.
出处
《现代临床医学生物工程学杂志》
2003年第5期405-406,409,共3页
Journal of Modern Clinical Medical Bioengineering
