摘要
目的 探讨儿童食管炎的发病、临床特征及其诊断治疗。方法 对 12 5例食管炎患儿的内镜表现、临床特征和幽门螺杆菌 (H .pylori)感染情况进行分析。 结果 4 0 32例胃镜检查病例中 ,诊断为食管炎者 12 5例(3 1% )。H .pylori阳性总例数 74 5 ,阳性率 18 5 % (74 5 / 4 0 32 ) ,其中非食管炎者阳性 72 1例 ,阳性率 18 5 %(72 1/ 390 7) ,食管炎者阳性 2 4例 ,阳性率 19 2 % (2 4 / 12 5 ) ,两者阳性率差异无显著性 (P >0 0 5 )。食管炎临床表现呕吐 5 5 2 % (6 9/ 12 5 ) ,胸痛 2 0 8% (2 6 / 12 5 ) ,嗳气 2 2 4 % (2 8/ 12 5 ) ,不同年龄组三种症状比较差异有显著性(P <0 0 5 ) ;腹痛 4 4 0 % (5 5 / 12 5 ) ,咽部不适 14 4 % (18/ 12 5 ) ,不同年龄二种症状比较差异无显著性 (P >0 0 5 )。内镜下病变全部局限食管下段 ,表现为充血、糜烂和渗出 ,未见溃疡、狭窄和局部组织及食管下段毛细血管增生 ,未检出食管裂孔疝 ;Ⅰ级 116例 ,占 92 8% (116 / 12 5 ) ,Ⅱ级 8例 ,占 6 4 % (8/ 12 5 ) ,Ⅲ级 1例 ,占 0 8%(1/ 12 5 ) ,各年龄组分级差异无显著性 (P >0 0 5 )。结论 广州地区儿童上消化道疾病H .pylori检出率为18 5 % ,食管炎患儿H .pylori感染与其他上消化道疾病相近 ;儿童食管炎占上?
Objective To study the clinical and endoscopic features and treatment of esophagitis in children.Methods The clinical manifestations and endoscopic features of 125 children with esophagitis were studied.Helicobacter pylori (H.pylori) was determined. Results The overall incidence of esophagitis was 3 1%(125/4032).The total positivity rate of H.pylori was 18 5%(745/4032);the positivity rates of H pylori of esophagitis and the rest cases were 19 2%(24/125) and 18 5% (721/3907).There was no significant differences between the two positivity rates (P>0 05).Esophagitis with symptoms (vomiting,chest pain,belching) was 55 2%(69/125),20 8%(26/125),and 22 4%(28/125),respectively;the symptoms were significantly different in different age groups(P<0 05).Abdominal pain and pharyngoxerosis were 44 0%(55/125) and 14 4%(18/125),and there was no significant difference between age groups(P>0 05).The lesion was in lower esophagus.Endoscopic features were erosion,congestion and effusion,but without ulcerstenosis,or capillary proliferation.No hiatal hernia was found.There were grade Ⅰin 116(92 8%),grade Ⅱ in 8(6 4%) and grade Ⅲ in 1(0 8%).There was no significant difference in lesion degrees between different age groups(P>0 05).Conclusion The positivity rate of H.pylori of upper gastrointestinal disease is 18 5% in children in Guangzhou.There is no significant difference between the positivity rates of H.pylori of esophagitis and the other upper gastrointestinal diseases.The incidence of esophagitis in children in Guangzhou is 3 1%.Vomiting is the major symptom of esophagitis in infants,while abdominal pain is in pre school age children.
出处
《中国实用儿科杂志》
CSCD
北大核心
2003年第9期543-545,共3页
Chinese Journal of Practical Pediatrics