摘要
目的:总结原发性中枢神经系统淋巴瘤的临床表现,探讨放射外科治疗效果。方法:应用伽玛刀放射外科治疗32例经病理证实的原发性中枢神经系统淋巴瘤患者。结果:系统随访30例患者,伽玛刀治疗后1～2个月肿瘤消失,症状迅速改善。术后的生存时间为1～34个月,平均15.5个月。结论:原发性中枢神经系统淋巴瘤诊断一旦明确,单发或2个病灶者,行伽玛刀和地塞米松治疗,症状改善后再行化疗和/或全脑放疗。这种治疗方案不良反应轻。
Objective To review the clinical manifestation of primary central nervous system lymphoma and to assess the role of the Gamma knife radiotherapy in the treatment of primary central nervous system lymphama. Methods Thirty-two patients with pathology proven primary central nervous system lymphama were treated with Gamma knife radiotherapy. Results Thirty patients were followed up after treatment. All lesions treated with Gamma knife radiotherapy diminished in size or disappeared within one or two months after treatment,and the neurological deficits had improved dramatically. The survival time of the thirty patients after Gamma knife radiotherapy treatment was 1 to 34 months with mean 15. 5 months. Conclusion After diagnosis has been made of primary central nervous system lymphama,single or two focus can be treated by Gamma knife radiotherapy and dexamethasone. When the patient's clinical symptoms are improved,chemotherapy and radiotherapy should be conducted. The treating programme has less side effect.
出处
《实用诊断与治疗杂志》
2003年第6期464-465,467,共3页
Journal of Practical Diagnosis and Therapy
