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雌激素及其受体对心血管系统保护作用实验研究进展 被引量:11

Protective effects of estrogen and estrogen receptor on the cardiovascular system in women
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摘要 雌激素对心血管系统具有重要的保护作用。雌激素及其受体主要通过调节血管舒张功能、抑制血管平滑肌细胞增殖和迁移以及影响肾素 -血管紧张素等介导这一保护作用。但临床上雌激素替代治疗尚未得到肯定 。 Estrogen has an important protective effects on the cardiovascular system in women. Estrogen and estrogen receptors(ER) take the protective effects by inhibiting vascular smooth muscle cell proliferation and by modulating rennin angiotension system. It can provide theoretic supportment for estrogen replacement therapy and CHD prevention by studying the mechanism of estrogen and ER in postmenopausal women. Bet the efficacy of the therepy has not cmfirmed yet.
出处 《中国心血管杂志》 2003年第5期377-379,共3页 Chinese Journal of Cardiovascular Medicine
关键词 雌激素受体 基因多态性 心血管疾病 保护作用 Estrogen receptor Gene polymorphism Cardiovascular disease
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