摘要
目的 :阐述自然流产、男性无精子症、先天愚型以及其它病症 (畸形、肥胖等 )与染色体变异的关系 ,以便做出及时、准确诊断。方法 :人外周血淋巴细胞染色体 G显带的检测。结果 :受检5 94例中染色体异常 5 8例 (异常率 9.73% )。其中自然流产患者 2 62例 ,异常 1 8例 (异常率6.87% ) ;无精子症 2 1 5例 ,异常 2 6例 (异常率 1 2 .0 9% ) ;先天愚型 32例 ,异常 1 2例 (异常率37.5 % ) ;其它病症 (畸形、肥胖等 ) 85例 ,异常 2例 (异常率 2 .35 % )。结论 :染色体核型分析有助于自然流产。
Obective:To study on the relationship between spontaneous abortion, Azoospermia, Down syndrome or other illness ( lopsided, fat etc.) and chromosome variation, in order to make accurate diagnosis. Methods: Chromosome of peripheral blood lymphocytes were performed to analysis the abnormal karyotypes in 594 patients. Results:Chromosome abnormal rate was 9.73% in 594 patients.In 262 spontaneous abortion patients, chromosome abnormal rate was 6.87%. In 215 Azoospermia, chromosome abnormal rate was 12.09%. In 32 Down symptom, chromosome abnormal rate was 37.5%. In 85 other illness (lopsided, fat etc.) patients, chromosome abnormal rate was 2.35%. Conclusion: Chromosome analysis technique has important application in cytogenesis etiology. [
出处
《吉林大学学报（医学版）》
CAS
CSCD
北大核心
2003年第5期570-572,共3页
Journal of Jilin University：Medicine Edition
基金
吉林省计划委员会资助课题 (1999)
关键词
自然流产
遗传学
少精子症
唐氏综合征
人染色体
核型分析
Abortion,spontaneous/genetils
Oligspermia/genetics
Down syndrome/genetics
Chromosome,human/genetics
Karyotype analysis
