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冠心病合并糖尿病患者冠脉病变与血清sLR11水平的关系 被引量:1

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摘要 目的探讨冠心病合并糖尿病患者冠脉病变情况与血清可溶性低密度脂蛋白受体(s LR11)水平的关系。方法选取2011年3月—2014年6月于该院心内科住院并行选择性冠状动脉造影检查的患者88例,根据血糖水平及冠脉造影结果将所有患者分为三组:正常组(29例)、单纯冠心病组(28例)和冠心病合并糖尿病组(31例)。对所有患者的冠脉病变情况采用Gensini评分系统进行评判,同时测定患者血清s LR11的水平,将冠脉病变情况与血清s LR11水平进行相关性分析。结果冠心病合并糖尿病组血清s LR11水平最高,为(36.45±10.31)ng/m L,其次为单纯冠心病组,为(27.39±8.17)ng/m L,正常组最低,为(15.47±9.12)ng/m L,三组间比较差异均有统计学意义(P<0.05);冠心病合并糖尿病组血清s LR11水平与患者Gensini评分呈正相关,r=0.631(P<0.05),而单纯冠心病组患者血清s LR11水平与Gensini评分具有一定正相关关系,但差异不具有统计学意义,r=0.334(P>0.05)。结论冠心病合并糖尿病患者血清s LR11水平与冠脉病变严重程度密切相关,提示s LR11可能成为冠心病合并糖尿病患者评价冠脉病变的新型指标及靶向治疗的新指标。
出处 《糖尿病新世界》 2014年第10X期18-18,共1页 Diabetes New World Magazine
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