摘要
目的 :通过同期对照研究 ,评价卒中高危人群筛选与重点干预策略实施的效果。 方法 :选择上海市南汇区作为干预区 ,从 35岁及以上人群中根据危险因素暴露情况筛选出易感人群 ,实施一般干预措施 ,再以脑血管血流动力学指标 (CVHI)检测筛选出高危人群 ,实施脑安胶囊重点干预措施。选择与南汇区毗邻的奉贤区 6个镇作为对照区。干预 3年期间同期随访监测干预区与对照区的卒中发生和死亡情况。 结果 :干预区和对照区的卒中发病率分别为 82 .30 / 1 0万和 1 5 0 .5 7/ 1 0万 ,死亡率分别为 6 3.39/ 1 0万和 1 2 9.72 / 1 0万 ,均有显著的统计学差异 (P <0 .0 1 )。干预区的发病率下降 4 5 .3% ,死亡率下降 5 1 .2 %。 结论
Objective:To evaluate the effectiveness of high risk population screening and pivot intervention srtategy on prevention of stroke. Methods: Nanhui county of Shanghai was selected as the intervention area. Individuals of 35 years old or over with at least one risk factor exposure were screened and received general intervention measures.High risk individuals were screened by cerebral vascular hemodynamic indices(CVHI) check and received intervention measure of taking traditional Chinese medicine 'Nao'an Capsule'. Six towns in Fengxian County abut on Nanhui were selected as non intervention control areas. During 3 years intervention term, incidence and mortality of stroke in both counties were followed up. Results: Incidences of stroke in intervention and control area were 82.30/100 000 and 150.57/100 000, and mortalities of stroke were 63.39/100 000 and 129.72/100 000. The incidence and mortality decreased to 45.3% and 51.1%; both of the incidence and mortality were significantly different between 2 areas( P <0.01). Conclusion: Intervention strategy of high risk population screening and pivot intervention can result in significant decrease in incidence and mortality of stroke.
出处
《第二军医大学学报》
CAS
CSCD
北大核心
2003年第9期1000-1002,共3页
Academic Journal of Second Military Medical University
基金
上海市政府专项基金 (沪科合 99第 0 0 5号 )
关键词
脑卒中
高危人群
危险因素
干预
上海
对照研究
stroke
high risk population
risk factor
intervention trial
control trial
