摘要
目的 探讨食管癌淋巴结转移的临床病理相关因素。方法 对204例食管癌根治标本进行统计,分析各主要临床病理改变与淋巴结转移关系。结果 204例食管癌中有淋巴结转移者89例,淋巴结转移率为43.6％。胸中段癌淋巴结转移率为48.0％,胸上段癌和胸下段癌的淋巴结转移率分别为32.0％和26.9％。髓质型和溃疡型淋巴结转移率分别为47.6％和56.0％,除缩窄型外其他类型转移率最高者为21.4％。男性患者淋巴结转移率为54.3％,女性淋巴结转移率为28.4％。浸润至黏膜层和黏膜下层者,未发现淋巴结转移,浸润至浅肌层、深肌层、纤维膜者淋巴结转移率分别为28.6％、45.6％和48.8％。以上四种因素中前后两者间比较差异均有显著性(P<0.05)。淋巴结转移率与年龄无关,也不随肿瘤大小的增加而增加。结论 男性食管胸中段癌患者淋巴结转移率较高,尤其当肿物为髓质型和溃疡型时最为显著。
Objective To evaluate the clinicopathological factors of lymph node metastasis of esophageal carcinoma.Methods 204 resected esophageal cancer specimens were carefully examined pathologically to seek the correlation between pathologic change and lymph node metastasis. Results Eighty-nine of 204(43.6%) had lymph node metastasis. There was obvious difference in metastasis rate between the patients with lesions in middle thoracic segment and those with lesions in other positions( P < 0.025) . The difference in rate of lymph node metastasis (RLM) was distinct between medullary type and other types, so did the ulcerative type( P < 0.005). RLM was obviously different between males and females( P < 0.005) . Difference in RLM was also seen among patients with different infiltrating depths,but this phenomena was not seen among different ages and different neoplasm size. Conclusion There is higher rate of lymph node metastasis in males with lesion in middle thoracic segment, especially the neoplasms of medullary type or ulcerative type.
出处
《中国肿瘤临床与康复》
2003年第4期316-318,共3页
Chinese Journal of Clinical Oncology and Rehabilitation
