摘要
目的 :了解直肠癌术前动脉插管化疗的病理组织学疗效。方法 :采用Seldinger法 ,对 10 0例直肠癌患者分别行 1~ 2次术前动脉插管化疗 ,末次化疗后 7~ 10d行手术治疗 ,切除标本进行病理组织学疗效分析。结果 :化疗后临床症状减轻 ,肿瘤体积缩小 ,手术切除率提高 ,切除标本病理组织学疗效分析 :轻效 5 4 % ,轻显效 32 % ,显效 8% ,总有效率 94 %。结论 :术前动脉插管化疗对直肠癌具有明显疗效。
Objective: To observe the pathohistological effects of pre-operation chemotherapy. Methods: 100 patients with rectal carcinoma were treated with chemotherapy via arterial catheterization for 1 or 2 times before operation.Operation was performed at 7~10 days after the last chemotherapy and samples were studied pathohistologically. Results: Tumor size was reduced by pre-operation chemotherapy and resectable rate was increased.Post-operation pathohistological examination revealed that the total effective rate was 94%. Conclusion: Significant therapeutic effects has been obtained by pre-operation chemotherapy via arterial catheterization in patients with rectal carcinoma.
出处
《中国新药杂志》
CAS
CSCD
北大核心
2003年第8期652-653,共2页
Chinese Journal of New Drugs
关键词
直肠癌
动脉插管化疗
病理组织学疗效
rectal carcinoma
chemotherapy via arterial catheterization
pathohistologic effectiveness