摘要
目的 :探讨新生儿窒息患儿血清总胆汁酸浓度的变化及临床应用。方法 :采用OLYMPUSAU 4 0 0 (日本 )全自动生化分析仪 ,对 86例新生儿窒息患儿和 34例正常对照新生儿进行空腹血清总胆汁酸 (TBA)测定 ,同时对其他肝功能相关指标进行测定。结果 :新生儿窒息患儿血清TBA与对照组相比呈显著性升高 (P <0 0 0 1 ) ;血清TBA与本组的血清谷丙转氨酶 (ALT)、碱性磷酸酶 (ALP)、r 谷氨酰转移酶 (r GT)、总胆红素 (TBIL)、直接胆红素 (DIBL)的检测水平有良好的相关性。治疗后的新生儿窒息患儿血清TBA水平下降趋向正常。结论 :血清TBA是一项灵敏的肝功能指标 。
Objective:To study the change of serum total bile acids(TBA) in the new born babies with asphyxia and its clinical application.Methods:Using autobiochemistry analyse instrument(made in Japan) with the analyse method of enzyme,the serum TBA in 86 new born babies suffering from asphyxia and 34 normal new born babies(control group),and the other indicator of liver function were detected.Results:The serum TBA of new born babies with asphyxia was significantly increased compared with the control group,and the level of serum TBA was correlated to that of ALT?ALP?r GT?TBIL?DIBL in the same group.The level of serum TBA of the children suffering from asphyxia dropped to normal after treatment.Conclusion:The serum TBA is a sensitive indicator for detecting liver function,especially has clinical significance to the diagnosis and treatment of the new born babies with asphyxia that result in liver damage,and is useful for the prognostic observation.
出处
《广西医学》
CAS
2003年第9期1589-1591,共3页
Guangxi Medical Journal
关键词
新生儿窒息
血清总胆汁酸测定
肝脏损害
预后
Total bile acids
New born baby with asphyxia
Analyse method of enzyme
