摘要
目的了解微生物源抗菌肽类药物研发领域现状,为该领域内企业的研发方向提供思路建议。方法基于专利视角,对全球数据库进行专利申请趋势分析,专利竞争格局分析,专利技术主题分析。结果总体来讲国外对于抗菌肽的研究集中于抗菌肽制品及应用,国内则较为重视抗菌肽的制备技术。国外技术的发展趋于成熟,处于稳定期,创新主体对中国市场十分重视。结论建议企业在此领域研发具有独特性质的复合抗菌肽,开发高纯度抗菌肽并实现规模生产,同时注重抗菌肽的检测方法的开发,并在研发过程中合理利用现有技术。
Objective To knowthe current situation of research and development of microbial-derived antimicrobial peptides and to provide suggestions for the enterprises in this field.Methods Based on the patent perspective,the patent application trend,patent competition pattern and patent technology theme of the global database were analyzed.Results In general,the researches on antimicrobial peptides abroad focused on antimicrobial peptides products and whose applications,while the preparation of antimicrobial peptides was paid more attention to in China.The development of foreign technologies tends to be mature and stable,and the innovator pay more attention to the Chinese market.Conclusion It is suggested that enterprises to develop compound antimicrobial peptides with special characters,and high-purity antimicrobial peptides,to realize large-scale production,as well as developing of test methods for antimicrobial peptides,and the existing technologies should be well considered in the process of research and development.
作者
周捷
宁静
于伟
王淑华
胡卫国
ZHOU Jie;NING Jing;YU Wei;WANG Shuhua;HU Weiguo(North China Pharmaceutical Co.Ltd,Shijiazhuang 050015,China;Dawei computer software development Co.Ltd.,Baoding 071000,China)
出处
《沈阳药科大学学报》
CAS
CSCD
北大核心
2019年第8期750-754,共5页
Journal of Shenyang Pharmaceutical University
关键词
微生物源抗菌肽
专利技术分析
研发
microbial antimicrobial peptide(MAP)
patent technology analysis
R&D
