摘要
目的探讨重度宫颈上皮内瘤变(CIN)的临床特点及诊治方法。方法回顾性分析2012年1月至2013年2月在南京市妇幼保健院阴道镜下活检诊断为CINⅢ的72例患者的临床资料,采用自身对照法,对阴道镜下活检病理、宫颈锥切术后病理以及子宫切除术后病理行对照研究。结果宫颈锥切术与阴道镜下检查的病理结果完全符合者54例(75%),不符合者18例(25%)。锥切术后病理诊断级别下降者16例(22.2%),浸润癌2例(2.8%)。34例患者再次行子宫切除术,其中27例(79.41%)术后病理转阴,7例病理诊断级别降低。结论宫颈锥切术是CINⅢ首选的治疗方法。是否进一步治疗应根据患者年龄、切缘状态、生育要求等多方面个体化、综合考虑以决定。
Objective To explore the clinical features and the treatment of severe cervical intraepithelial neoplasia.Methods The clinical data of 72 cases of CIN Ⅲ diagnosed by colposcopic biopsy in Nanjing Maternity and Child Health Care Hospital from January 2012 to February 2013 were retrospectively analyzed.The pathology results of colposco-pic biopsy,cervical conization and further hysterectomy were compared and analyzed.Results Of all the 72 patients,the pathology results of 54 cases(75%) of cervical conization were in accord with colposcopic biopsy.Pathological diagno-sis level according to conization decreased in 16 cases(22.2%),and 2 cases were diagnosed as carcinoma(2.8%).Thirty-four patients underwent hysterectomy.The postoperative pathology turned negative in 27 cases(79.41%) and the pathological diagnosis level decreased in 7 cases.Conclusions Cervical conization is a preferred method for treatment of CIN Ⅲ.Further treatment should be based on the age of the patients,resection margin status,fertility requirements and other aspects of the patients.
出处
《实用老年医学》
CAS
2013年第12期1015-1017,共3页
Practical Geriatrics
关键词
重度宫颈上皮内瘤变
阴道镜
宫颈锥切术
severe cervical intraepithelial neoplasia
colposcopy
cervical conization
