摘要
目的分析宫颈癌治疗后下肢淋巴水肿的发生相关因素。方法回顾性分析218例宫颈癌患者的资料,通过统计学分析得出淋巴水肿的发生率及其相关因素。结果宫颈癌治疗后下肢淋巴水肿总发生率为19.3%。手术联合放疗的患者下肢淋巴水肿的发生率最高,为29.3%;单纯放疗组发生率为16.3%,单纯手术治疗组发生率为8.9%,三组之间差异具有统计学意义(P=0.014<0.05)。术中行淋巴结清扫的患者下肢淋巴水肿的发生率为27.9%,术中无淋巴清扫者为5.8%,两者比较差异具有统计学意义(P=0.008<0.05)。体外照射B点剂量>45 Gy的患者下肢淋巴水肿发生率为26.8%,体外照射B点剂量≤45 Gy者发生率为13.1%,差异具有统计学意义(P=0.038<0.05)。结论下肢淋巴水肿是宫颈癌患者治疗后的常见并发症之一;不同治疗方式淋巴水肿发生率不同,淋巴水肿的发生受多种因素影响,包括术后联用放疗及放疗剂量。
Objective To investigate the correlative factors of occurrence oflower limbs lymphedema( LLL) in cervical cancer patients after treatment. Methods Data of 218 cervical cancer patients were retrospectively studied,and the incidence of LLL and correlative factors were calculated. Results The incidence of LLL in patients with cervical cancer after treatment was19. 3%. Among all the patients who received different regimes,the incidence of LLL in patients with surgery combined with radiotherapy was the highest( 22 /75 cases,29. 3%); the incidence of LLL in patients who received simple radiotherapy was 16. 3%( 16 /98 cases); and the incidence of LLL in patients who received surgery alone was 8. 9%( 16 /98 cases). There had significant difference( P = 0. 014 < 0. 05). Among the patients who received lymphadenectomy during surgery,the incidence of LLL was27. 9%,and the incidence was 5. 8% among those who did not receive lymphadenectomy,and there had significant difference( P= 0. 008 < 0. 05). For the patients who received radiotherapy,the incidence of LLL was 26. 8% among those whose pelvic dose at point B was more than 45 Gy,while the incidence was 13. 1% when the dose was not more than 45 Gy,there had significant difference( P = 0. 038 < 0. 05). Conclusion LLL is one of the most common complications in cervical cancer patients after treatment.The incidence of LLL differs with different treatment methods. LLL is influenced by multiple factors such as radiotherapy combined with surgery,and the dose of external irradiation.
出处
《实用癌症杂志》
2015年第1期108-111,共4页
The Practical Journal of Cancer
关键词
宫颈癌
下肢淋巴水肿
Cervical cancer
Lower limb lymphedema(LLL)
