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妊娠高血压综合症患者血清尿酸浓度检测及其临床价值

Clinical Significance of Plasma Uric Acid Measurement in Pregnancy Induced Hypertension
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摘要 目的:探讨妊娠高血压综合症患者血尿酸浓度检测的临床价值。方法:采用尿酸酶法检测156例妊高症的血尿酸(UA)浓度,同时观测各组间出生时低产龄儿发生率、孕龄和出生体重百分位数以及围产儿结局的差别。结果:出生时胎龄≤4周和≤2周的平均发生率为:HPU组比HP组明显增高,HU组明显比HP组增高,HU组比H组明显增高。HPU组明显比NNN组高,但是在NNN组和HP组之间没有区别。各组孕龄比较:HPU组比HP组孕妇生产日期平均提前3.6周(35.4±3.7vs 39.0±1.5),HU组比HP组分娩日期平均提前2.5周(36.5±2.0 vs 39.0±1.5),HU组比H组孕妇分娩日期平均提前2.9周(36.5±2.0 vs 39.4±1.5)。结论:血UA水平反映了妊高症疾病严重程度,可作为判断孕妇早产和胎儿预后的生化指标。 Objective:To investigate the clinical significance of serum uric acid measurement in pregnancy induced hypertension (PIH) patients.Methods:For the 156 YIH patients,the serum uric arid was tested with uricase assay,meanwhile we observe the difference of the incidence of small-for-gestational age (SGA),gestational age at delivery,the birth weight centile and the outcome of perinatal period infant between the groups.Results: HPU group is significantly higher than the HP group,HU group is much higher than the HP group,HU group is significantly higher than the H group,but there is no difference between NNN group and HP group.The contrast of the gestational age when birth between the groups:compared with pregnancies with HP,pregnancies with HPU delivered an average of 3.6 weeks earlier(35.4±3.7 vs 39.0±1.5),HU group delivered an average of 2.5 weeks earlier than HP group(36.5±2.0 vs 39.0±1.5),HU group delivered an average of 2.9 weeks earlier(36.5±2.0 vs 39.4±1.5) than H group.Conclusion:The serum uric acid levels are believed to be the reflection of patients in progression of PIH and can be used as a biochemical marker for judging the fetal outcome.
作者 朱红琼
出处 《临床医药实践》 2008年第13期347-349,共3页 Proceeding of Clinical Medicine
关键词 妊娠并发症 高血压 尿酸 pregnancy complication hypertension unc acid
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参考文献4

  • 1Redman CW,Beilin LJ,Bonnar J,Wilkinson RH.Plasma-urate measurements in predicting fetal death in hypertensive pregnancy[].The Lancet.1996 被引量:1
  • 2Bar J,,OrvietoR.Pregnancy outcome in women with primary renal disease[].The Israel Medical Association Journal.2002 被引量:1
  • 3Roberts,JM,Creasy,RK,Resnik,R.Pregnancy related hypertension[].Maternal Fetal Medicine.1998 被引量:1
  • 4Lim,KH,Friedman,SA,Ecker,JL.The clinical utility of serum uric acid measurements in hypertensive diseases of pregnancy[].American Journal of Obstetrics and Gynecology.1998 被引量:1

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