摘要
[目的]系统评价艾灸治疗糖尿病高危足的有效性,为糖尿病高危足的治疗及预防提供参考意见。[方法]计算机检索Cochrane Library、JBI、PubMed、EMbase、中国生物医学文献数据库(CBM)、中国知网(CNKI)、万方数据知识服务平台(WanFang Data)、维普期刊资源整合服务平台(VIP)数据库中有关艾灸治疗糖尿病高危足的随机对照试验(RCT)和半随机对照实验(CCT),检索时间限定为各数据库建库至2016年5月1日。由2名研究员按照纳入及排除标准进行文献筛选并提取资料,并参考Cochrane手册的质量评价标准对纳入文献进行质量评价,利用RevMan 5.3分析软件进行Meta分析。[结果]最终共纳入9篇原始研究,其中8篇RCT,1篇CCT,合计875例病人。文献质量等级为B级的原始研究数量为7篇,C级2篇。Meta分析结果显示:艾灸治疗能够有效改善糖尿病高危足所致的下肢疼痛、神经反射异常、感觉功能异常、麻木的症状[MD=-1.69,95%CI(-2.36,-1.02),P<0.000 01];艾灸能够有效改善糖尿病高危足病人的正中神经运动传导速度[MD=2.82,95%CI(1.55,4.09),P<0.000 1];艾灸能够改善糖尿病高危足病人踝肱指数[MD=0.15,95%CI(0.04,0.27),P=0.008]。[结论]艾灸可以改善糖尿病高危足的神经传导速度及血液循环流速,预防糖尿病足溃疡的发生。
Objective:To evaluate the effectiveness of moxibustion therapy for patients with high-risk diabetic foot,and to provide reference for its treatment and prevention.Methods:Randomized controlled trial(RCT)and semi-randomized controlled trials(CCT)articles on moxibustion therapy for patients with high-risk diabetic foot were searched in Cochrane Library,JBI,PubMed,EMbase,China Biomedical Literature Database(CBM),China Knowledge Network(CNKI),Wanfang Data Knowledge Service Platform(WanFang Data),Weipu Periodical Resource Integration Service Platform(VIP)from database construction to May 1,2016.Data were collected and extracted by two researchers according to the inclusion criteria,and the quality of the literatures was evaluated by reference to the quality evaluation criteria of the Cochrane Handbook.Meta-analysis was performed by using Review Manger 5.3analysis software.Results:A total of 9pieces of literatures were included in this study,in which 8RCTs and 1CCT,involving 875 patients.There was 7Grade B quality of original research and papers 2Grade C quality of original research papers.Meta-analysis showed that:moxibustion treatment could effectively improve lower extremity pain,abnormal nerve reflex,sensory dysfunction,and numbness symptoms caused by high-risk diabetic foot[MD=-1.69,95%CI(-2.36,-1.02),P<0.000 01];moxibustion could effectively improve the median motor nerve conduction velocity in patients with high-risk diabetic foot[MD=2.82,95%CI(1.55,4.09),P<0.000 1];moxibustion could effectively improve the ABI of patients with high-risk diabetic foot[MD =0.15,95%CI(0.04,0.27),P=0.008].Conclusions:Moxibustion could improve the NCV and blood circulation velocity of high-risk diabetic foot,and prevent the occurrence of diabetic foot ulcer.
出处
《护理研究（上旬版）》
2017年第8期2718-2724,共7页
Chinese Nursing Researsh
基金
北京中医药大学中青年教师专项课题
编号:2015-JYB-JSMS068
关键词
糖尿病高危足
艾灸
系统评价
糖尿病周围神经病变
糖尿病血管病变
high-risk diabetic foot
moxibustion
systematic review
diabetic peripheral neuropathy
diabetic vascular disease
