摘要
裂谷热(Rift Valley fever,RVF)是由裂谷热病毒(Rift Valley fever virus,RVFV)引起的发热性人兽共患病,该病导致反刍动物的大面积死亡及人类的致命性出血热。RVF最初仅流行于非洲东部地区,现正在逐步扩大。2016年我国确诊首例输入性病例,提示非流行地区和国家正在面临威胁。RVF的流行不仅严重影响人类的健康及畜牧业的发展,更可能被用作潜在生物战剂,因此被世界动物卫生组织列为必须报告疫情。本文对RVF的流行病学、分子生物学、检测技术及疫苗研究进展等方面进行简要综述,为今后RVF的相关研究提供参考。
Rift Valley fever(RVF)is a fever amphixenosis caused by Rift Valley fever virus(RVFV). It leads to massive death of ruminants and fatal hemorrhagic fever in humans. The virus was restricted to the eastern region of Africa initially,while is in spreading at present. The first imported case was diagnosed in China in 2016,suggesting a threat to nonepidemic countries or regions. The epidemic of RVF not only seriously influencs the health of humans and the development of animal husbandry,but also might be used as a potential biological warfare,thus has been listed to the notifiable epidemics by the OIE. This paper reviews the epidemiology,molecular biology and detection technology of RVF as well as the progress in vaccine research,so as to provide a reference for further research on RVF.
作者
毕津豪
闫飞虎
黄培
赵永坤
杨松涛
BI Jin-hao;YAN Fei-hu;HUANG Pei;ZHAO Yong-kun;YANG Song-tao(College of Animal Science,Jilin Agricultural University,Changchun 130118,Jilin Province,China)
出处
《中国生物制品学杂志》
CAS
CSCD
2019年第3期351-356,共6页
Chinese Journal of Biologicals
基金
边境地区外来动物疫病阻断及防控体系研究(2017YFD-0501804)
关键词
裂谷热病毒
流行病学
分子生物学
检测技术
疫苗
Rift Valley fever virus(RVFV)
Epidemiology
Molecular biology
Detection technology
Vaccine
