期刊文献+

浅谈药物合成结晶技术分析与探讨 被引量:2

Analysis and Discussion on the Crystallization Technology of Drug Synthesis
下载PDF
导出
摘要 科学技术的飞速发展,促进了药物生产技术的快速进步。药物合成是一种十分重要的药物生产技术。药物合成后处理是药物生产一个不可忽视的步骤。获得药物纯品需要在药物合成过程中做好药物合成后处理工作,才可以进一步实现药品的医疗质量。本文主要就药物合成生产中的结晶技术进行探讨,介绍了药物结晶过程中的一些特征及新工艺的应用。 With the rapid development of modern medical technology, it promotes the rapid progress of drug production technology. Drug synthesis is an important drug production technology. Drug synthesis drug synthesis postprocessing is a noticeable step, has an important influence on drug synthesis. To obtain pure drug need in the process of drug synthesis in drug synthesis postprocessing work, can achieve further drug tone quality. This paper mainly discussed the crystallization technology of drug synthesis, combination of theory and application, and introduced some characteristics of drug crystallization process and new technology.
作者 阚晓臣
出处 《生物化工》 2016年第2期69-70,73,共3页 Biological Chemical Engineering
关键词 药物合成 结晶 纯化 Drug synthesis Crystallization Purification
  • 相关文献

参考文献4

二级参考文献13

  • 1Casey CP, Beetner SE, Johnson JB. Spectroscopic determination of hydrogenation rates and intermediates during carbonyl hydro- genation catalyzed by Shvo's hydroxycyclopentadienyl diruthenium hydride agrees with kinetic modeling based on independently measured rates of elementary reactions [ J ]. J Am Chem Soc, 2008, 130(7) :2285-2295. 被引量:1
  • 2Payette JN, Yamamobo H. Nitrosobenzene-mediated C#C bond cleavage reactions and spectral observation of an oxazetidin-4-one ring system[J]. J Am Chem Soc, 2008, 130(37):12276- 12278. 被引量:1
  • 3Hossain MS, Schwan AL. Separate deprotonation reactions con- verge mechanistically for a new cyclization of benzyl 1-alkynyl sulfones[ J]. Org Lett, 2011, 13(19) :5330-5333. 被引量:1
  • 4Dabrowski JA, Moebius DC, Wommack AJ, et al. Catalytic and regioselective ring expansion of aryleyelobutanones with trimethyl- silyldiazomethane ligand-dependent entry to p-ketosilane or enol- silane adducts[J]. Org Lett, 2010, 12(16) :3598-3601. 被引量:1
  • 5Reichardt R, Yagin S, Reithmeier R, et al. Factors influencing the ring-opening polymerization of racemic β-butyrolactone using CrⅢ (salphen) [ J ]. Macromolecules, 2010, 43 ( 22 ) : 9311- 9317. 被引量:1
  • 6Van Humbeck JF, Simonovich SP, Rnowles RR, et al. Concern- ing the mechanism of the FeC13-catalyzed r-oxyamination of alde- hydes: evidence for a non-SOMO activation pathway[ J]. J Am Chem Soc, 2010, 132(29) :10012-10014. 被引量:1
  • 7Kajita Y, Rusahashi T, Matsnbara S. Nickel-catalyzed decarbon- ylative addition of anhydrides to alkynes [ J ]. J Am Chem Soc, 2008, 130(51 ) :17226-17227. 被引量:1
  • 8Watkins AL, Landis CR. Origin of pressure effects on regioselec- tivity and enantioselectivity in the rhodium-catalyzed hydroformy- lation of styrene with ( S, S, S)-bisdiazaphos [ J ]. J Am Chem Soc, 2010, 132(30) :10306-10317. 被引量:1
  • 9Liu J, Deng Y, Wang H, et al. Effective Pd-nanoparticle (PdNP) - catalyzed Negishi coupiing involving alkylzinc reagents at room temperature [ J ]. Org Lett, 2008, 10 ( 13 ) :2661-2664. 被引量:1
  • 10Zhao Y, Jin L, Li P, et al. Palladium-catalyzed oxidative car- bonylation of alkyl and aryl indium reagents with CO under mild conditions[J]. J Am Chem Soc, 2008, 130(29) :9429-9433. 被引量:1

共引文献4

同被引文献7

引证文献2

二级引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部