摘要
目的:观察参芪固本汤治疗慢性阻塞性肺疾病(COPD)稳定期肺肾气虚证患者的临床疗效。方法:将符合纳入标准的70例COPD稳定期肺肾气虚证患者随机分为治疗组和对照组,每组各35例。两组患者均给予西医常规治疗,治疗组患者在西医常规疗法基础上加用参芪固本汤口服,两组疗程均为6个月。疗程结束后评价并比较两组的主要症状疗效、中医证候疗效及肺通气功能指标[包括1秒用力呼气容积(FEV1)/用力肺活量(FVC)、FEV1占预计值百分比(FEV1%)、FVC]。结果:治疗后,治疗组的主要症状疗效总有效率为94.3%,对照组为74.3%,两组比较差异有统计学意义(P<0.05)。治疗后,治疗组的中医证候疗效总有效率为97.1%,对照组为77.1%,两组比较差异有统计学意义(P<0.01)。治疗后,两组患者的FEV1%、FEV1/FVC水平均明显升高(P<0.05),且治疗组患者的FEV1%、FEV1/FVC水平高于对照组(P<0.05)。结论:参芪固本汤结合西医常规疗法治疗COPD稳定期肺肾气虚证患者,可有效控制临床症状,改善肺功能,值得在临床中推广、应用。
Objective: To observe the efficacy of "Shenqi Guben Decoction " in the treatment of chronic obstructive pulmonary disease( COPD) at stable stage with syndrome of qi deficiency in lung and kidney. Methods: Seventy patients of COPD at stable stage who met the inclusion criteria were randomly divided into the treatment group and control group,35 cases in each group. All the patients were treated with conventional western medicine and the patients in the treatment group were treated with "Shenqi Guben Decoction"orally in addition,with a course of 6 months. The symptomatic efficacy,Chinese medical syndrome efficacy and the pulmonary ventilation function indexes( including FEV1/FVC,FEV1% and FVC) were evaluated and compared. Results: After treatment,the total effective rates on the main symptoms in the treatment group and the control group were 94.3% and 74.3% respectively,with statistical difference between the two groups( P<0.05). After treatment,the total effective rates on the Chinese medical syndrome in the treatment group and the control group were 97.1% and 77.1% respectively,with statistical difference between the two groups( P<0.01). After treatment,the levels of FEV1% and FEV1/FVC in both groups were obviously increased( P<0.05),and the levels of FEV1% and FEV1/FVC in the treatment group were higher than those in the control group( P < 0.05). Conclusion: "Shenqi Guben Decoction " combined with conventional western medicine can effectively relieve the clinical symptoms and improve the pulmonary ventilation function in patients of COPD at stable stage with syndrome of qi deficiency in lung and kidney,which is worthy of promotion in clinic.
出处
《上海中医药大学学报》
CAS
2018年第1期27-29,共3页
Academic Journal of Shanghai University of Traditional Chinese Medicine
基金
上海中医药大学课程建设项目(JX2016077)
关键词
慢性阻塞性肺疾病
稳定期
肺肾气虚证
参芪固本汤
中西医结合疗法
chronic obstructive pulmonary disease
stable stage
syndrome of qi deficiency in lung and kidney
Shenqi Guben Decoction
integrated Chinese and western medicine therapy
