摘要
目的:通过观察补阳还五汤联合脑血管二级预防对脑卒中患者神经功能恢复的临床疗效,探讨联合疗法对脑卒中患者的预后影响。方法:选取自2012年3月~2014年12月入我院治疗的脑卒中后患者117例,根据其入院治疗时间分为观察组57例,联合治疗组60例。观察组给予常规西医治疗,主要目的为改善微循环、控制脑部水肿、扩张血管、营养脑细胞以及抗血管痉挛等。联合治疗组在观察组治疗基础上,以补阳还五汤为主方,采用中药颗粒制剂,同时联合脑血管相关二级预防为治疗手段,以10天为1个疗程,连续治疗3个疗程。记录两组各自有效率,同时应用神经功能缺损程度评分(NDS)、功能综合评定量表(FCA)和改良巴氏指数(BI)的参数指标评定神经功能改善情况,对两组患者治疗前、治疗后15天以及治疗后30天(M0、M1、M3)的临床疗效进行分析。结果:联合治疗组较观察组疗效明显增强(P<0.05),差异有统计学意义;联合治疗组M1、M3的BI、FCA增高及NDS降低均较观察组明显。两组患者M1、M3的BI、FCA均较M0有所增高(P<0.05),DNS有所降低(P<0.01),差异有统计学意义,联合治疗组治疗一周后血清hs-CRP及WBC水平显著低于观察组,差异有统计学意义(P<0.05)。结论:补阳还五汤联合脑血管二级预防与传统的常规西医治疗均可促进脑卒中患者的神经功能恢复,但补阳还五汤联合脑血管二级预防在脑卒中患者神经功能改善、修复方面的优势更为明显,临床中可作为脑卒中患者神经功能修复的辅助治疗手段而予以推广应用。
Objective: Observing the effect of Buyang Huanwu Decoction combined with cerebrovascular secondary prevention for neural functional recovery in patients with cerebral apoplexy,and to study the effect of the combination therapy on the prognosis of patients with cerebral apoplexy. Methods: Selecting 117 cases patients after stroke in our hospital from March 2012 to December 2014,according to the hospitalized time divided into observation group and controlled group,57 cases were in the obserbation group and 60 cases in the combined treatment group. The observation group was given conventional western medicine treatment,the main purpose for improving microcirculation,controlling brain edema,dilating blood vessels,brain cells and nutrition vasospasm,etc. The combined treatment group was given Buyang Huanwu Decoction,the formulas for traditional Chinese medicine granules,joint cerebrovascular related secondary prevention for treatment at the same time,in a month for a period of treatment,treatment of three consecutive period of treatment. Two groups of individual efficiently,and at the same time the application degree of nerve function defect score( NDS),functional comprehensive assessment scale( FCA) and the parameters of the improved pap index( BI) assess neurologic improvement,before and after treatment in patients with two groups of 1 month and 3 months after treatment( M0,M1,M3) of clinical efficacy were analyzed. The levels of serum hs-CRP and WBC in the combined treatment group were significantly lower than those in the observation group after treatment,the difference was statistically significant( P<0. 05). Results: The curative effect of the combined treatment group obviously increased compared with the observation group( P<0. 05),the difference was statistically significant; The combined treatment group increased BI,FCA of M1,M3 and NDS reduced obviously in the observation group. Two groups of patients with M1,M3 BI,FCA than M0 increase significantly( P<0. 05),the DNS had decreased( P<0. 01),the difference wa
出处
《四川中医》
2017年第9期93-96,共4页
Journal of Sichuan of Traditional Chinese Medicine
关键词
补阳还五汤
脑血管二级预防
脑卒中
神经功能恢复
Buyang Huanwu Decoction
Cerebrovascular secondary prevention
Stroke
Neural functional recovery
