摘要
目的 建立复方阿司匹林片中低浓度阿司匹林的溶出度测定方法。方法 采用将溶出液中的阿司匹林全部水解成水杨酸后用高效液相色谱法测定。结果 该法消除了复方成分双嘧达莫的干扰。结论 该法操作简便 ,结果正确。
OBJECTIVE To establish the dissolution determination method of low dose asprin in compound asprin tablets. METHOD An HPLC method was developed to determine the salicylic acid, a product after hydrolysis of asprin.RESULTS The average recovery ratio and RSD for asprin were 100.2% and 1.2% respectively. CONCLUSION This method is simple, rapid and accurate.
出处
《中国现代应用药学》
CAS
CSCD
北大核心
2003年第4期308-310,共3页
Chinese Journal of Modern Applied Pharmacy
