摘要
目的 :探讨免疫反应在冠心病中的作用。方法 :5 8例患者经冠状动脉造影后分为 4组 :心肌梗塞 (AMI)组 15例、不稳定性心绞痛 (UAP)组 10例、稳定性心绞痛 (SAP)组 11例与冠脉造影正常的对照组 2 2例 ,测定血清免疫球蛋白IgG、IgA、IgM和补体C3、C4 的水平。结果 :AMI组的IgG、IgA、补体C3、C4 的水平明显高于SAP组和对照组 (P <0 .0 5 ) ;UAP组的IgG和C3水平也明显高于SAP组和对照组 (P <0 .0 5 ) ;SAP组与对照组之间IgG、IgA、补体C3、C4 的水平及各组间IgM水平比较无显著性差异 (P >0 .0 5 )。结论 :IgG、IgA、C3、C4 的水平增高与冠心病有一定的联系 。
Objective:To study the relationship between immunoreaction and coronary heart disease(CHD).Methods:The levels of immunoglobulin(IgG?IgA?IgM)and complement(C 3?C 4)were measured in 58 patients given angiography,the patients were divided into 4 groups:15 cases of myocardial infarction(AMI);10 cases of unstable angina pectoris(UAP);11 cases of stable angina pectoris(SAP)and 22 cases of normal control.Results:The levels of IgG?IgA?and C 4 in AMI group and the level of IgG and C 3 were significantly higher than those in SAP and control groups.While the levels of IgG?IgA?and C 4 between SAP and control groups,the levels of IgM in all groups showed no significant difference.Conclusion:The incidence of CHD is correlated with the elevation of IgG?IgA?C 3 and C 4.and the immunoreaction may participate in the generation and progress of CHD.
出处
《赣南医学院学报》
2003年第3期274-276,共3页
JOURNAL OF GANNAN MEDICAL UNIVERSITY
