摘要
目的:了解血浆置换过程中SEN病毒(SENV)感染情况及对重型肝炎患者肝脏病变的影响。方法:采用套式聚合酶链反应(nPCR)检测慢性重型乙型肝炎患者血浆置换前后血清中SENV DNA并对检测结果和临床资料进行统计学分析。结果:30例慢性重型乙型肝炎患者血浆置换前后SENV检出率分别为10％(3/30)和36.7％(11/30),两组比较差异有显著性意义。30例SENV阳性和阴性患者之间,各项肝功能指标比较,差异均无显著性意义。结论:SENV可通过血浆置换方式传播,但混合SENV感染不影响慢性重型肝炎患者肝脏病变。
Objective: To investigate the prevalence of SENV infection during plasma exchange on chronic hepatitis gravis and its effect on liver function. Methods: SENV-D and SENV-H DNA were detected and comparison of effect of SENV infection on liver function was made before and after the treatment of plasma exchange. Results: SENV-DNA positive rates were 10% (3/30) and 36.7% (11/30) in chronic severe hepatitis before and after the treatment of plasma exchange respectively, there was no significant difference between groups of SEN virus infection, and non-infection. Conclusion: Plasma exchange is high risk factor for SENV infection SENV is not a causative agent of chronic hepatitis gravis.
出处
《中西医结合肝病杂志》
CAS
2003年第4期198-199,共2页
Chinese Journal of Integrated Traditional and Western Medicine on Liver Diseases
基金
湖北省科委资助(No:2002AA301C32)
