摘要
目的:观察复方苦参汤对熏洗治疗痔术后并发症的临床疗效。方法:将痔术后患者223例随机分为观察组111例,对照组112例;2组均给予相同的基础治疗及手术方式,术后观察组患者予复方苦参汤对患部进行熏洗,对照组予聚维酮碘液坐浴治疗;于术后第2、3、5、7天时观察患者肛门疼痛的情况并进行评分,检测患者血清肿瘤坏死因子α(TNF-α)、白细胞介素-1(IL-1)、白细胞介素-6 (IL-6)水平,评价2组临床疗效,统计创面愈合时间。结果:总有效率观察组为94.59%,对照组为83.04%,2组比较,差异有统计学意义(P <0.05)。术后第2天,2组疼痛VAS评分比较,差异无统计学意义(P> 0.05);术后第3、5、7天,观察组疼痛VAS评分均低于对照组,差异有统计学意义(P <0.05)。治疗后,观察组患者疼痛、肛门坠胀感消退时间及创面愈合时间均短于对照组,差异有统计学意义(P <0.05)。治疗后,2组血清TNF-α、IL-1、IL-6含量均较治疗前明显下降(P <0.05),且观察组各项指标水平下降较对照组更显著(P <0.05)。结论:复方苦参汤熏洗治疗痔术后并发症疗效显著,并可明显改善患者血清炎症因子水平,值得临床推广应用。
Objective:To observe the clinical effect of Fufang Kushen tang in fumigation and washing for hemorrhoids postoperative complications.Methods:Divided 223 cases of patients randomly into the observation group(111 cases)and the control group(112 cases).The two groups were given the same basic treatment and operation.After treatment,the patients in the observation group were treated with Fufang Kushen tang in fumigation and washing for the anal affected area,and the patients in the the control group were treated with povidone-iodine solution in sitz bath.Observed and scored the anal pain on the 2nd,3rd,5th and 7th postoperative day after treatment,and detected the levels of serum tumor necrosis factorα(TNF-α),interleukin-1(IL-1),and interleukin-6(IL-6),and evaluated the clinical effect of the two groups and counted the complete healing time of the wound.Results:The total effective was 94.59%in the observation group and 83.04%in the control group,compared the two groups,difference being significant(P<0.05).On the 2nd day after operation,there was no significant difference being found in the VAS scores between the two groups(P>0.05).On the 3rd,5t hand 7th day after operation,the VAS scores of the observation group were lower than those of the control group,difference being significant(P<0.05).After treatment,the pain,anal bulging sensation time and wound healing time of the observation group were shorter than those of the control group,difference being significant(P<0.05).After treatment,the levels of serum TNF-α,IL-1 and IL-6 in the two groups were significantly decreased when compared with those before treatment(P<0.05);the levels of each index in the observation group were evidently lower than those in the control group(P<0.05).Conclusion:The application of Fufang Kushen tang in fumigation and washing has obvious curative effect in treating hemorrhoids postoperative complications and can significantly improve the levels of serum inflammatory factors in patients.It is worthy of clinical promotion and application.
出处
《新中医》
CAS
2019年第4期169-171,共3页
New Chinese Medicine
关键词
痔术后并发症
肛门疼痛
复方苦参汤
中药熏洗
Hemorrhoids postoperative complications
Anal pain
Fufang Kushen tang
Chinese herbal fumigation and washing
