摘要
目的:观察养肝滋肾、清热解毒法治疗抗精子抗体(AsAb)阳性、抗子宫内膜抗体(EMAb)阳性所致免疫性不孕症的疗效。方法:对204例AsAb阳性、282例EMAb阳性患者应用养肝滋肾汤(处方:紫河车、党参、紫石英、白术、山药、淫羊藿、菟丝子、当归、生地黄、熟地黄、龟板、徐长卿、黄柏)内服;清热解毒汤(处方:苦参、黄连、秦艽、苍术、徐长卿、黄柏、龙胆草、玄参)坐浴治疗。观察用药后AsAb、EMAb转阴及妊娠情况。结果:AsAb阳性患者2疗程转阴188例(92.16％),4疗程转阴8例,合计转阴196例(96.08％);EMAb阳性患者2疗程转阴230例(81.56％),4疗程转阴20例,合计转阴250例(88.65％)。196例AsAb转阴患者,治疗后跟踪6个月经周期,妊娠136例(69.38％);250例EMAb转阴患者,治疗后跟踪6个月经周期,妊娠228例(91.2％),未发生流产。结论:养肝滋肾、清热解毒法治疗免疫性不孕症效果较好,转阴率、妊娠率高,无毒副作用。
Objective: To observe the therapeutical principle of nourishing liver and kidney, clearing heat and removing toxic substance (NCR) for immune sterility with positive antisperm antibody(AsAb) and anti -endometrium antibody (EMAb) . Methods: 204 cases with positive AsAb and 282 cases with opsitive EMAb were treated by oral use of Decoction of Nourishing Liver and Kidney (composed of Placenta Hominis, Radix Codonopsis, Fluoritum, Rhizoma Atractylodis Macro-cephalae, Rhizoma Dioscoreae, Herba Epimedii, Semen Cuscutue, Radix Angelicae Sinensis, Radix Rehmanniae, Radix Rehmanniae Preparata, Carapax et Plastrum Testudinis, Radix Cynanchi Paniculati and Cortex Phellodendri)and Decoction of Clearing Heat and Removing Toxic Substance (composed of Radix Sophorae Flavescentis; Rhizoma Coptidis, Radix Gentianae Macrophyllae, Rhizoma Atractylodis, Radix Cynanchi Paniculati, Cortex Phellodendri, Radix Gentianae and Radix Scrophulariae) for sitz bath. After medication, the turning negative of AsAb, EmAb and occurence of prognancy were observed. Results: After 2 and 4 courses of treatment, AsAb turned negative in 188 cases (92. 16% )and 8 cases respectively, totally 196 cases(96. 08% ); and EMAb turned negative in 230 cases(81. 56% ) amd 20 cases respectively totally 250 casess(88. 65% ). A follow - up of 6 menstrual cycles showed 136 cases(69. 38% )were pregnant in 196 cases when AsAb turned negative, and 228 cases (91. 2% )became pregnant in 250 cases when EMAb turned negative, and no miscarriage was observed. Conclusion: The above treatment has a good effect for immune sterility with high turning negative rate of relevant antibodies and pregnant rate, and no toxix and side effects were observed.
出处
《新中医》
CAS
北大核心
2003年第8期23-24,共2页
New Chinese Medicine
基金
山东省济宁市科技局课题(编号:济科字02012)
