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大剂量甲氨蝶呤治疗骨肉瘤的毒副反应及防治 被引量:6

Side effects and prevention due to high-dose methotrexate in osteosarcoma patients
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摘要 大剂量甲氨蝶呤(MTX)化疗,可导致造血系统损害、消化系统反应、肝肾损害等严重不良反应。如何应对不良反应的发生,将患者的痛苦减至最小是化疗成功的关键问题之一。本文根据有关文献并结合临床实际探讨大剂量MTX治疗骨肉瘤所致毒副反应及防治措施。
作者 张威 何绥平
出处 《药物不良反应杂志》 2003年第4期238-240,共3页 Adverse Drug Reactions Journal
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