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重症牙周炎龈组织内浆细胞的超微结构观察

Ultrastructural Study on the Plasma Cell in Human Gingival Tissue of Periodontitis
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摘要 对14例(男3,女11,年龄24~60岁)临床诊断为重症牙周炎累及的龈组织透射电镜观察的结果表明,龈上皮有增生性变化。基层有增厚以及局部消失和重复。固有层内胶原原纤维变性明显,浸润炎症细胞中以浆细胞(PC)数量最多且变性显著。根据PC的核、质膜和特别是粗面内质网池等超微结构变性的程度,将PC分为4期:1期属正常PC,2、3和4期为变性PC。从粗面内质网池内容物电子密度的变化、鲁氏体数量的增减和胶原原纤维的变性等现象上看,本文认为成人牙周炎有体液免疫参与。 Fourteen cases (3males, 1females, aged24 to 60 years)of periodontitis-affected gingival tissue were studied using transmission electron microscopy. The results showed that the epithelium has hyperplasia. The basal lamina became thickening and has disappearance and reduplication. The collagen fibrils in Lamina were markedly degenerated. The number of plasma cells (PC)was the most in infiltrated inflammatory cells and showed significant ultrastructural variations. According to their variation degree of ultrastructural features of muclei,plasma membrane and especially cisternae of rough endoplasmic reticulum (RER)PC were classified as 4 stages. Stage 1 PC had normal ultrastructural appearance. And stages 2,3 and 4 PC were degenerated. In the light of change of density of RER cotent, increase and decrease of Russell's bodies number and degeneration of collagen fibrils, this paper suggests that the adult periodontitis is related to the humoral immunity.
作者 李树侃 冯利
出处 《兰州医学院学报》 1992年第4期228-231,共4页 Journal of Lanzhou Medical College
关键词 牙周炎 龈组织 超微结构 浆细胞 Periodontitis Gingival tissue Ultrastrueture Plasma cell Humoral immunity
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