摘要
目的了解中山市2010—2015年双相情感障碍住院患者的临床特征、诊断变化趋势等相关因素,为双相情感障碍的治疗提供依据。方法采用回顾性调查方法,对2010年1月1日—2015年12月31日在中山市第三人民医院住院的双相情感障碍患者进行资料收集,包括性别、年龄、婚姻等人口学资料以及发病年龄、确诊年龄、既往诊断、首次发作形式、发作次数、住院次数、治疗情况、出院诊断等临床资料。结果共收集688例双相情感障碍患者。(1)平均首次发病年龄为(21.46±5.78)岁,63.37%的患者首次发作为抑郁发作,确诊年龄为(28.34±6.12)岁;(2)发病年龄最高峰在20~29岁,为268(38.95%)例,30~39岁年龄段次之,为214(31.1%)例;(3)双相情感障碍的诊断率依次为11.24%、12.38%、13.56%、14.12%、14.39%、15.11%,平均诊断率为13.51%,其中双相情感障碍躁狂发作最多,占53.49%,其他依次为双相障碍抑郁发作占34.3%,混合发作占9.3%;(4)双相情感障碍患者病情反复发作,其中大多数患者发作2~5次,大多数患者住院次数为2次以上。结论双相情感障碍住院患者发病年龄早,首发发作多为抑郁症状,住院患者以青壮年(20~39岁)最多,其中双相障碍躁狂发作最多,病情反复发作,导致患者反复多次住院。近6年双相情感障碍的诊断率基本呈逐年增高趋势,说明临床医生对双相情感障碍的认识不断提高。
Objective To investigate the clinical features and factors related with diagnosis in inpatients with bipolar disorder in Zhongshan city from 2010 to 2015,and provide evidence for the treatment of bipolar disorder.Methods All inpatient with bipolar disorder who has been hospitalized in the third people’s hospital of Zhongshan city from Jan,1 st 2010 to Dec 31 th 2015 were enrolled in the study.Retrospective investigation was used to collect the demographics data including sex,gender,marriage and the clinical information including the age of onset,age of diagnosis,previous diagnosis,first form of attack,frequency of attack,number of hospitalization,treatment and discharge diagnosis and so on.Results 688 inpatient with bipolar disorder were enrolled the study.The average age of onset was 21.46±5.78 years old,the average age of diagnosis was 28.34±6.12 years old,depressive episode was the first onset in 63.7%of bipolar inpatients.The onset peak age was ranged from 20 to 29 years old,there were 268(38.95%)cases of inpatients were in this age range.There were 214(31.1%)inpatients between 30 and 39.Diagnosis rates of bipolar disorder of the 6 age period were11.24%,12.38%,13.56%,14.12%,14.39%and 15.11%,the average rate of diagnosis was 13.51%,the rate of bipolar disorder of manic episode was53.49%,depressive episode was 34.3%and the mixed episode was 9.3%.Patients with bipolar disorder suffered recurrent attacks,most patients had 2 to 5 episodes and hospitalized more than 2 times.Conclusions Patients with bipolar disorder often onset early and the depressive episode is the most common first episode.Patients are mainly young people(20~39 years old)and the manic episode accounts for the most among the bipolar disorder hospitalized in our hospital.They suffered from recurrent attacks,and hospitalized more than 2 times.The diagnosis of bipolar disorder showed a trend of increase year by year,which is perhaps concerned with the improvement of the clinical psychiatrists’identify ability of bipolar disorder.
作者
刘磊
陈贻华
蒋廷云
肖翠琪
LIU Lei(The first people's hospital of Guangzhou,Guangzhou,Guangdong,510180,China)
出处
《齐齐哈尔医学院学报》
2019年第5期611-613,共3页
Journal of Qiqihar Medical University
基金
中山市社会发展攻关计划(医疗)(2015B1147)
关键词
双相情感障碍
发病年龄
诊断率
临床特征
Bipolar disorder
Age of onset
Diagnosis rate
Clinical features
