摘要
目的 探讨原发性肾病综合征 (PNS)并发急性肾功能衰竭 (ARF)的诱因、治疗方法及预后。方法 回顾分析近 6a间 35 6例PNS中并发ARF 35例患者的临床特征、治疗方法和预后情况。 35例PNS并ARF患者 ,随机分为治疗组 (A组 )2 0例 ,甲基强的松龙联合低分子右旋糖酐加速尿 ;对照组 (B组 ) 15例 ,甲基强的松龙联合间歇输注人体白蛋白后加速尿。结果 PNS并发ARF的发生率为 10 .17%。A组与B组比较 ,ARF好转率、PNS总缓解率无显著性差异 (P >0 .0 5 )。结论 甲基强的松龙联合低分子右旋糖酐加速尿抢救PNS并ARF患者疗效确切 ,经济实用 ,副作用小。
Objective To analyse the therapy and prognosis of primary nephrotic syndrome(PNS) accompanied with acute renal failure (ARF). Methods 365 PNS patients had 35 patients with ARF. The patients accompanied with acute renal failure were randomly divided into two groups. The A group included 20 patients who were treated with methylprednisolone, low molecular dextran and furosemide. The B group included 15 patients who were treated with methylprednisolone, personal albumin and furosemide. Results The incidence rate of primary nephritic syndrome accompanied with acute renal failure was 10.17%. There was no difference between two groups in therapeutic efficacy (P>0.05). Conclusion The therapeutic efficacy of methylprednisolone, low molecular dextran and furosemide to primary nephritic syndrome accompanied with acute renal failure were effective , and there were little adverse effect events.
出处
《中国急救医学》
CAS
CSCD
北大核心
2003年第8期552-553,共2页
Chinese Journal of Critical Care Medicine
