摘要
目的探讨术中冰冻病理检查对甲状腺微小乳头状癌的病理诊断价值。方法选择本院收治的甲状腺微小乳头状癌患者45例作为资料进行研究,均获取术中冰冻标本,进行回顾性分析,与常规石蜡切片进行比较,观察冰冻切片的病例诊断价值。结果术中冰冻病理检出率为77.78%,肿瘤直径为(0.56±0.05)cm,且边界不清晰;冰冻切片光镜下甲状腺组织为异型细胞团巢,可观察到明显的浸润行为、核异型和核内假包涵体等。结论在甲状腺微小乳头状癌诊断中行术中冰冻病理检查可快速诊断,且准确率较高,但需仔细观察形态特征进行明确,避免出现漏诊。
OBJECTIVE To investigate the value of intraoperative frozen pathological examination in the pathological diagnosis of thyroid micropapillary carcinoma.METHODS The diagnostic value of frozen section was compared with that of conventional paraffin section.RESULTS The detection rate of frozen pathology during operation was 77.78%.The diameter of tumor was(0.56±0.05)cm,and the boundary was not clear.Under the light microscope of frozen section,thyroid tissue is a nests of abnormal cells,and obvious infiltrating behavior,nuclear heterogeneity and intranuclear pseudoinclusion body can be observed.CONCLUSIONS Intraoperative frozen pathological examination can be used to diagnose thyroid micropapillary carcinoma quickly and accurately,but it is necessary to observe the morphological features carefully to avoid missed diagnosis.
出处
《中华肿瘤防治杂志》
CAS
北大核心
2018年第S1期39-40,共2页
Chinese Journal of Cancer Prevention and Treatment
关键词
术中冰冻病理检查
甲状腺微小乳头状癌
诊断价值
intraoperative frozen pathological examination
thyroid micropapillary carcinoma
diagnostic value
