摘要
目的研究甘肃中西部地区HPV感染与宫颈癌的临床相关性。方法采用HPV检测及分型,选取正常宫颈组织、宫颈慢性炎症组织、宫颈癌,对HPV感染率进行对比,进而对宫颈癌组织中HPV感染及高危型HPV16、18型与宫颈癌进行临床相关性研究。结果宫颈癌组织中HPV感染率明显高于正常宫颈及宫颈慢性炎症组织,经统计学分析,具有显著性差异(P<0.05);不同宫颈组织中HPV感染与年龄相关,(P<0.05);宫颈癌组织中,HPV感染率与宫颈癌级别相关,(P<0.05);宫颈癌组织中高危型HPV16、18感染与宫颈癌的分级明显相关(P<0.05)。结论甘肃中西部地区HPV感染与宫颈癌的发病、年龄及级别,具有临床相关性。
OBJECTIVE To explore the clinic correlation between the HPV infection and cervical cancer in the middle and western areas of Gansu.METHODS To use the methods of HPV detection and classification,compare the HPV infection rate of the normal cervical tissue,chronic inflammatory tissue,cervical cancer tissue;further to study the linic correlation of HPV infection,high-risk HPV 16,18 of the cervical cancer tissue.RESULTS The infection rate of in cervical cancer tissue s obviously high in the the normal cervical tissue,chronic inflammatory tissue(P<0.05),the infection of HPV in different tissue is relate to the age(P<0.05),the infection rate of HPV is relate to the grade of the cervical cancer(P<0.05),the infection rate of high-risk HPV infection rate of HPV is relate to the grade of the cervical cancer(P<0.05).CONCLUSIONS The infection rate of HPV is obviously relate to the age,grade of the cervical cancer.
出处
《中华肿瘤防治杂志》
CAS
北大核心
2018年第S1期1-2,共2页
Chinese Journal of Cancer Prevention and Treatment
关键词
宫颈癌
HPV
cervical carcinoma
HPV
