摘要
目的 :分析体外受精与胚胎移植 (IVF ET)治疗不孕症 2 90个周期的效果。方法 :采用GnRHa/FSH/hCG和GnRHa/FSH/hMG/hCG两种超促排卵方案 ,对 2 5 2对不孕夫妇共进行了 2 90个周期常规IVF、冻融胚胎或卵胞浆内单精子显微注射 (ICSI)及胚胎移植 (ET)治疗。结果 :合计 2 90个周期共获临床妊娠 10 5例 ,周期妊娠率为36 .2 %。流产 9例 ,异位妊娠 11例 ,已分娩 6 5例 ,获新生儿 91个 ,另 2 0例继续妊娠。按女性年龄 <30岁、30～ 34岁、35～ 39岁、≥ 4 0岁分为 4个年龄组 ,4组的周期妊娠率依次为 4 7.0 %、34.1%、2 5 .5 %、0 ,有统计学差异 (P <0 .0 5 )。结论 :不孕夫妇用常规IVF、冻融胚胎移植或ICSI后均能获得较好的妊娠效果。
Objective:To review the results of 290 cycles In Vitro Fertilization and Embryo Transfer(IVF ET).Methods:Total 252 couples(290 cycles)were accepted for treatment by conventional IVF,frozen thawed embryo or ICSI.The protocol of controlled superovulation was GnRHa/FSH/hMG/hCG or GnRHa/FSH/hCG.Results:There were three groups:conventional IVF,frozen thawed embryo and ICSI groups. Two hundred and ninety cycles were divided into four groups by female age(<30,30～34, 35～39,≥40 years old),respectively.The total clinical pregnancies were 105 cases and clinical pregnancy rate of per ET cycles was 36.2% from 290 cycles.From a total of 105 pregnancies,9 patients had spontaneous abortion,11 had ectopic pregnancy,65 had delivery of 91 liveborn babies and 20 were ongoing pregnancy.The clinical pregnancy rate was 47.0%,34.1%,25.5% and 0.0%,respectively.There was a significant difference( P <0.05).Conclusion:Couples with female or male infertility have good pregnancy rates after conventional IVF, frozen thawed embryo or ICSI,and the clinical pregnancy rate of per cycle is closely related with the female age.
出处
《实用临床医学（江西）》
CAS
2003年第4期77-80,共4页
Practical Clinical Medicine
关键词
体外受精
胚胎移植
冷冻胚胎
卵胞浆内单精子注射
fertilization in vitro
embryo transfer
frozen thawed embryo
intracytoplasmic sperm injection
