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曲马多与哌替啶用于硬膜外麻醉病人术中及术后寒颤治疗的比较

Comparison of effectiveness of tramadol and pethidine used for shivering during perioperations
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摘要 目的 评价曲马多与哌替啶在治疗硬膜外麻醉中出现的寒颤效果。方法 将60例在硬膜外阻滞下行下腹手术且发生了寒颤的病人(ASAⅠ~Ⅱ级)随机分为三组:A组,静脉注入生理盐水5ml;B组:经静脉注入哌替啶0.5mg/kg;C组,经静脉注入曲马多1mg/kg,分别记录用药前及用药后1、 3、5min寒颤评分及各组出现的不良反应。结果 A组治疗前后寒颤评分无显著差别,B组和C组均于治疗5min后寒颤停止;A组和C组均未出现恶心,呕吐等副作用,而B组中恶心,呕吐,呼吸抑制,嗜睡等副作用均有数例。结论曲马多1mg/kg经静脉注射与哌替啶0.5mg/kg经静脉注射相比更适于用来处理硬膜外阻滞下出现的寒颤。 Objective To evaluate the effectiveness of tramadol and pethidine used for shivering during perioperations. Methods 60 patients (ASA Ⅰ -Ⅱ) who underwent epidural anaesthesia and shivering during perioperations were divided reandomly into three groups, Group A:saline 5ml was injected via vein; Group B:pethidine 0.5mg/kg was injected via vein; Group C:tramadol 1mg/kg was injected via vein. Record the scores of shivering at the time before the treatment and at the 1st,3rd,5th min after the tratment. At the same time,record the adverse effects. Results There is no significant difference of the scores of shivering at each moment between Group B and Group C, at the 5th min shivering stopped in both Group B and Group C, but in Goup A,no significant difference was shown before and after the treatment In both Group A and Group C, no adverse effect was found,but in Group B,there were several adverse effects e-merged, which include: nausea,vomitting,respiratory, inhibition and somnolence. Conclusion Tramadol Img/kg via vein is better than pethidine 0.5mg/kg via vein for the treatment of the shivering during perioperations.
出处 《江西医药》 CAS 2003年第3期155-156,共2页 Jiangxi Medical Journal
关键词 曲马多 哌替啶 硬膜外麻醉 术中 术后 寒颤 治疗 比较 Tramadol Pethidine epidural block shivering
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