摘要
目的 :探讨轮状病毒 (rotavirus,RV)肠炎患儿血清中可溶性白介素 2受体 (SIL 2R)、白介素 6(IL 6)、白介素 8(IL 8)和肿瘤坏死因子α(TNF α)的变化 ,及其在发病中的免疫作用机制。方法 :采用双抗体夹心ELISA法 ,检测 5 0例RV肠炎患儿血清中SIL 2R、IL 6、IL 8及TNF α的水平 ,同期与病情变化及正常对照组比较。结果 :RV肠炎在急性期血清中SIL 2R、IL 6、IL 8及TNF α水平较正常对照组升高 (P <0 .0 1) ,与病情存在一定的相关关系。结论 :血清SIL 2R、IL 6、IL 8及TNF
Objective:To study the changes of SIL-2R,IL-6,IL-8 and TNF-α in children with rotavirus(RV) enteritis and their possible mechanism in immunnoregulation.Methods:The serum SIL-2R,IL-6,IL-8 and TNF-α in 50 children with RV enteritis were determined by sandwich ELISA method.Results:The serum SIL-2R,IL-6,IL-8 and TNF-α levels in children with RV enteritis were significantly increased and obviously correlated with the disease courses.Conclusion:It is possible that serum SIL-2R,IL-6,IL-8 and TNF-α may play an important role in immunoregulating mechanism in children with RV enteritis.
出处
《温州医学院学报》
CAS
2003年第4期237-238,共2页
Journal of Wenzhou Medical College
