摘要
目的探讨左旋氨氯地平治疗高血压的临床疗效。方法选取2015年1—5月贵州医科大学第二附属医院收治的高血压患者200例,按随机数字表法分为对照组与观察组,各100例。观察组患者予以左旋氨氯地平治疗,对照组患者予以尼群地平治疗。观察两组患者临床疗效、不良反应发生情况及治疗前后生活质量评分。结果两组患者临床疗效比较,差异无统计学意义(P>0.05);观察组患者不良反应发生率低于对照组,差异有统计学意义(P<0.05);治疗前两组患者躯体功能、角色功能、社会功能、情绪功能及总体评分比较,差异无统计学意义(P>0.05),治疗后观察组患者躯体功能、角色功能、社会功能、情绪功能及总体评分高于对照组,差异有统计学意义(P<0.05)。结论左旋氨氯地平治疗高血压的临床疗效显著,可提高患者的生活质量,且不良反应少。
Objective To explore the effect of L- Amlodipine in treating hypertension. Methods A total of 200 patients with hypertension were selected in the Second Affiliated Hospital of Guizhou Medical University from January to May2015,according to random number table method,they were divided into observation group and control group,100 cases in each group. Observation group were given L- Amlodipine treatment,control group were given nitrendipine treatment. Clinical effect,incidence of adverse reactions and before and after treatment life quality score between the two groups were compared. Results Clinical effect showed no significant differences between the two groups( P > 0. 05); incidence of adverse reactions of observation group were lower than those of control group( P < 0. 05); before treatment,body function,role function,social function,emotion function and overall score showed no significant differences between the two groups( P > 0. 05),after treatment,body function,role function,social function,emotion function and overall score of observation group were higher than that of control group( P < 0. 05). Conclusion L- Amlodipine has notable curative effect in the treatment of hypertension,can improve the life quality of patients and has less adverse reaction.
出处
《临床合理用药杂志》
2016年第6期8-9,共2页
Chinese Journal of Clinical Rational Drug Use
