摘要
目的探讨布地奈德混悬液联合孟鲁司特钠片治疗支气管哮喘的临床疗效。方法选取2012—2013年德阳市东汽医院收治的支气管哮喘患者78例,随机分成治疗组和对照组,每组39例。对照组给予布地奈德治疗,治疗组给予布地奈德联合孟鲁司特钠治疗。比较两组患者的临床疗效、第1秒用力呼气容积(FEV1)、用力肺活量(FVC)、呼气高峰流量(PEFR)。结果治疗前两组患者的FEV1、FVC和PEFR比较,差异无统计学意义(P>0.05);治疗后治疗组FEV1、FVE和PEFR高于对照组,差异有统计学意义(P<0.05)。治疗组总有效率高于对照组,差异有统计学意义(P<0.05)。结论布地奈德混悬液联合孟鲁司特钠片治疗支气管哮喘的临床疗效显著,可有效改善患者肺功能,且不良反应少。
Objective To explore the effect of budesonide suspension and montelukast sodium tablets in treating bronchial asthma. Methods A total of 78 patients with bronchial asthma were selected in the Dongqi Hospital of Deyang from 2012 to 2013,they were randomly divided into control group and treatment group,39 cases in each group. Control group were given budesonide suspension treatment, treatment group were given budesonide suspension and montelukast sodium tablets treatment. Clinical effect,forced expiratory volume in one second( FEV1),forced vital capacity( FVC),peek expiratory flow rate( PEFR) between the two groups were compared. Results Before treatment,FEV1,FVC and PEFR showed no significant differences between the two groups( P > 0. 05),after treatment,FEV1,FVC and PEFR of treatment group were higher than those of control group( P < 0. 05). The total effective rate of treatment group was higher than that of control group( P < 0. 05).Conclusion Budesonide suspension and montelukast sodium tablets have notable curative effect in the treatment of bronchial asthma,can effectively improve lung function and has less adverse reaction.
出处
《临床合理用药杂志》
2016年第3期13-14,共2页
Chinese Journal of Clinical Rational Drug Use
