摘要
目的 通过总结特发性肺纤维化 (IPF)患者的临床特点 ,提高对IPF诊断、治疗及管理的认识。方法 对 4 8例符合ATS/ERS提出的特发性肺纤维化诊断标准IPF患者进行回顾性分析。结果 4 8例IPF患者 (男∶女 =4 0∶8) ,均有咳嗽 ,伴进行性呼吸困难和Velcro罗音。X线表现为磨玻璃样、网状、结节状、条索状及蜂窝状阴影。肺功能检查示 38例限制性通气功能障碍 ,10例混合性通气功能障碍 ,均有弥散功能障碍。动脉血气分析示低氧血症、呼吸性碱中毒。经过综合治疗IPF患者短期内临床与肺功能大多有所改善 ,而远期疗效差 ,病死率高。结论 对长期咳嗽伴有呼吸困难的患者 ,及时行胸部X线、肺功能、动脉血气分析及肺活检 ,能对本病做出正确的诊断。对IPF患者实施全程的治疗观察 。
Objective To improve the cognition for the diagnosis,therapy and management of idiopathic pulmonary fibrosis(IPF) by summarizing its clinical features.Methods Retrospective analysis was conducted on 48 cases of IPF according to the diagnostic criteria formulated by the ATS/ERS.Results All the patients(male 40,female 8),aged 34～70 years with an average age of 62.4years, had an insidious onset of progressive dyspnea and nonproductive cough. Most of patients had finger clubbing and Velcro rale. X ray examination exhibited glassy, reticular, nodular, stripe and alveolate lesions. All the cases put up diffuse dysfunction by lung function examinations,and 38 of them had restrictive ventilation dysfunction and 10 of them had combined ventilation dysfunction. Arterial blood gas analysis indicated hypoxemia. Conclusion It is necessary to perform examinations such as chest Xray,pulmonary function,arterial blood gas analysis on patients with chronic cough and dyspnea in time for the diagnosis of IPF. It may benefit to the IPF patients for improvement their life and prognosis by being observed in the the whole period of therapy.
出处
《重庆医学》
CAS
CSCD
2003年第7期818-819,共2页
Chongqing medicine
关键词
特发性肺纤维化
临床表现
病理
诊断
治疗
idiopathic pulmonary fibrosis
clinical features
pathology
diagnosis
treatment
