摘要
目的 :探讨大肠腺瘤性息肉发生癌变的相关因素。方法 :对经结肠镜及病理检查确诊的 1 0 2 5例大肠腺瘤性息肉病例发生癌变的相关因素进行回顾分析。结果 :1 0 2 5例中 3 9例发生癌变 ,癌变率为 3 .8%。重度不典型增生和癌变的发生率 ,在≥ 40岁组显著高于 <40岁组 (P <0 .0 5 ) ,且与息肉的部位、大小及病理类型均显著相关 (均P <0 .0 5 )。息肉的直径与重度不典型增生及癌变率呈正比。结论 :大肠腺瘤性息肉癌变与其大小、部位、病理类型及患者的年龄等因素相关。
Objective:To investigate the factors associated with the cancerization of colorectal adenomatous polyp. Methods: To analyze the information of 1025 colorectal adenomatous polyp cases which were diagnosed by colonoscopy and pathology. Results: In all cases, the rate of cancerization was 3.8% (39 cases). As far as the rate of cancerization concerned, patients above 40 years old had a higher rates than those who less than 40. The female had a higher rate than the male. The rectal adenoma were more easy to change to malignacy than colon. The diameters of polyp had a positive correlation with cancerization. From the standpoint of pathology, the villous adenoma was more prone to develop into carcinoma than the tubular adenoma. Conclusion: Many factors, such as patient's age, the diameter and location of the polyp, were related to colorectal cancerization. The pathology pattern also played a role in it.
出处
《中日友好医院学报》
2003年第3期136-138,共3页
Journal of China-Japan Friendship Hospital
